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Chapter 16 - Benefits and Costs of the Malaria Targets for the Post-2015 Consensus Project

Published online by Cambridge University Press:  30 May 2018

Bjorn Lomborg
Affiliation:
Copenhagen Business School
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Summary

Despite a 42% decrease in global malaria mortality since 2000, the disease was estimated to cause 627,000 estimated deaths worldwide in 2012. 90% percent of all estimated deaths occurred in Sub-Saharan Africa and 77% were in children under five. Malaria-endemic countries also bear considerable indirect long-term costs associated with physical and cognitive retardation, malnutrition, anaemia and increased disease susceptibility. The past decade of malaria control has seen significant changes in antimalarial drug policies, mass distribution of insecticide-treated bed nets, and corresponding declines in the incidence of malaria (Fegan et al. 2007). A big push is being contemplated to eliminate malaria in areas of unstable transmission, with the eventual goal of global elimination (Smith et al. 2013). Here, we consider two targets that could be useful in the context of an overall malaria eradication strategy: A. Delay artemisinin resistance greater than 1% until 2025 through a combination of quality artemisinin combination therapies (ACTs), multiple first-line therapies (MFTs) and resistance containment efforts B. Reduce malaria incidence by 50% between 2015 and 2025 through mass distribution of long lasting insecticide treated bed nets (LLITNs)
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Prioritizing Development
A Cost Benefit Analysis of the United Nations' Sustainable Development Goals
, pp. 287 - 294
Publisher: Cambridge University Press
Print publication year: 2018

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References

Alonso, P. L., Lindsay, S. W., Armstrong Schellenberg, J. R. M., et al.A malaria control trial using insecticide-treated bed nets and targeted chemoprophylaxis in a rural area of The Gambia, West Africa 6. The impact of the interventions on mortality and morbidity from malaria.” Transactions of the Royal Society of Tropical Medicine and Hygiene 87, no. Supplement 2 (1993): 3744.CrossRefGoogle Scholar
Arrow, Kenneth J., Panosian, Claire, and Gelband, Hellen, eds. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance. Washington, DC: National Academies Press, 2004.Google Scholar
Arrow, Kenneth J., Gelband, Hellen, and Jamison, Dean T.. “Making antimalarial agents available in Africa.” New England Journal of Medicine 353, no. 4 (2005): 333–5.Google Scholar
Arrow, Kenneth J., Danzon, Patricia M., Gelband, Hellen, et al.The Affordable Medicines Facility—malaria: killing it slowly.” The Lancet 380, no. 9857 (2012): 1889–90.Google Scholar
Bacon, David J., Jambou, Ronan, Fandeur, Thierry, et al.World Antimalarial Resistance Network (WARN) II: in vitro antimalarial drug susceptibility.” Malaria Journal 6, no. 1 (2007): 120.CrossRefGoogle ScholarPubMed
Barat, Lawrence M.Four malaria success stories: how malaria burden was successfully reduced in Brazil, Eritrea, India, and Vietnam.” The American Journal of Tropical Medicine and Hygiene 74, no. 1 (2006): 1216.Google Scholar
Barnes, Karen I., Durrheim, David N., Little, Francesca, et al.Effect of artemether-lumefantrine policy and improved vector control on malaria burden in KwaZulu–Natal, South Africa.” PLoS Medicine 2, no. 11 (2005): e330.Google Scholar
Bhattarai, Achuyt, Ali, Abdullah S., Patrick Kachur, S., et al.Impact of artemisinin-based combination therapy and insecticide-treated nets on malaria burden in Zanzibar.” PLoS Medicine 4, no. 11 (2007): e309.CrossRefGoogle ScholarPubMed
Boni, Maciej F., Smith, David L., and Laxminarayan, Ramanan. “Benefits of using multiple first-line therapies against malaria.” Proceedings of the National Academy of Sciences 105, no. 37 (2008): 14216–21.Google Scholar
Bosman, Andrea, and Mendis, Kamini N.. “A major transition in malaria treatment: the adoption and deployment of artemisinin-based combination therapies.” The American Journal of Tropical Medicine and Hygiene 77, no. 6 Suppl (2007): 193–7.CrossRefGoogle Scholar
Breman, Joel G., Mills, Anne, Snow, Robert W., et al.Conquering malaria” in Jamison, D. R., Breman, J. G., Measham, A. R., et al. (eds.), Disease Control Priorities in Developing Countries, 2nd ed. (New York: Oxford University Press, 2006): 413–32. Available: www.dcp-3.org/sites/default/files/dcp2/DCP21.pdf. Accessed November 1, 2014.Google Scholar
Chizema-Kawesha, Elizabeth, Miller, John M., Steketee, Richard W., et al.Scaling up malaria control in Zambia: progress and impact 2005–2008.” The American Journal of Tropical Medicine and Hygiene 83, no. 3 (2010): 480–8.Google Scholar
Cohen, Jessica, and Dupas, Pascaline. “Free distribution or cost-sharing? Evidence from a randomized malaria prevention experiment.” Quarterly Journal of Economics 125, no. 1 (2010): 1.Google Scholar
Dapeng, Luo, Renguo, Yao, Jinduo, Song, Hongru, Huo, and Wang, Ze. “The effect of DDT spraying and bed nets impregnated with pyrethroid insecticide on the incidence of Japanese encephalitis virus infection.” Transactions of the Royal Society of Tropical Medicine and Hygiene 88, no. 6 (1994): 629–31.Google Scholar
Dondorp, Arjen M., Fairhurst, Rick M., Slutsker, Laurence, et al.The threat of artemisinin-resistant malaria.” New England Journal of Medicine 365, no. 12 (2011): 1073–5.CrossRefGoogle ScholarPubMed
Fegan, Greg W., Noor, Abdisalan M., Akhwale, Willis S., Cousens, Simon, and Snow, Robert W.. “Effect of expanded insecticide-treated bednet coverage on child survival in rural Kenya: a longitudinal study.” The Lancet 370, no. 9592 (2007): 1035–9.Google Scholar
Fumiya, Shiga, Chongsvivatwong, Virasakdi, Saburo, Uchiyama, and Thammapalo, Suwich. “The feasibility of a bed net impregnation program to enhance control of Malayan filariasis along a swamp forest in southern Thailand.” Southeast Asian Journal of Tropical Medicine and Public Health 32, no. 2 (2001), 235239.Google Scholar
Goodman, C. A. “The economic evaluation of malaria diagnosis.” Draft Position Paper prepared for informal consultation on “Malaria diagnostics at the turn of the century.” organized by WHO and USAID, Geneva (1999): 25–7.Google Scholar
Guerin, Philippe J., Olliaro, Piero, Nosten, Francois, et al.Malaria: current status of control, diagnosis, treatment, and a proposed agenda for research and development.” The Lancet Infectious Diseases 2, no. 9 (2002): 564–73.Google Scholar
Guerin, Philippe J., Olliaro, Piero, Nosten, Francois, et al.Malaria: current status of control, diagnosis, treatment, and a proposed agenda for research and development.” The Lancet Infectious Diseases 2, no. 9 (2002): 564–73.Google Scholar
Guillet, Pierre, N’guessan, R., Darriet, Frédéric, et al.Combined pyrethroid and carbamate ‘two-in-one’ treated mosquito nets: field efficacy against pyrethroid-resistant Anopheles gambiae and Culex quinquefasciatus.” Medical and Veterinary Entomology 15, no. 1 (2001): 105–12.CrossRefGoogle ScholarPubMed
Hawley, William A., Phillips-Howard, Penelope A., ter Kuile, Feiko O., et al.Community-wide effects of permethrin-treated bed nets on child mortality and malaria morbidity in western Kenya.” The American Journal of Tropical Medicine and Hygiene 68, no. 4 suppl (2003): 121–7.Google Scholar
Jonkman, A., Chibwe, R. A., Khoromana, C. O., et al.Cost-saving through microscopy-based versus presumptive diagnosis of malaria in adult outpatients in Malawi.” Bulletin of the World Health Organization 73, no. 2 (1995): 223.Google ScholarPubMed
Laxminarayan, Ramanan, Parry, Ian W. H., Smith, David L., and Klein, Eili Y.. “Should new antimalarial drugs be subsidized?Journal of Health Economics 29, no. 3 (2010): 445–56.Google Scholar
Laxminarayan, Ramanan. “Act now or later? Economics of malaria resistance.” The American Journal of Tropical Medicine and Hygiene 71, no. 2 suppl (2004): 187–95.CrossRefGoogle ScholarPubMed
Lengeler, Christian. “Insecticide-treated bed nets and curtains for preventing malaria.” Cochrane Database Syst Rev 2, no. 2 (2004).Google Scholar
Lourens, Chris, Watkins, William M., Barnes, Karen I., et al.Implementation of a reference standard and proficiency testing programme by the World Wide Antimalarial Resistance Network (WWARN).” Malaria Journal 9 (2010): 375.Google Scholar
Mills, Anne, and Shillcutt, Sam. The Challenge of Communicable Diseases. (Tewksbury, MA: Copenhagen Consensus, 2004).Google Scholar
Morel, Chantal M., Lauer, Jeremy A., and Evans, David B.. “Cost effectiveness analysis of strategies to combat malaria in developing countries.” BMJ 331, no. 7528 (2005): 1299.Google Scholar
Otten, Mac, Aregawi, Maru, Were, Wilson, et al.Initial evidence of reduction of malaria cases and deaths in Rwanda and Ethiopia due to rapid scale-up of malaria prevention and treatment.” Malaria Journal 8, no. 1 (2009): 14.Google Scholar
Rolland, Estelle, Checchi, Francesco, Pinoges, Loretxu, et al.Operational response to malaria epidemics: are rapid diagnostic tests cost-effective?Tropical Medicine & International Health 11, no. 4 (2006): 398408.CrossRefGoogle ScholarPubMed
Ross, Amanda, Maire, Nicolas, Sicuri, Elisa, Smith, Thomas, and Conteh, Lesong. “Determinants of the cost-effectiveness of intermittent preventive treatment for malaria in infants and children.” PloS One 6, no. 4 (2011): e18391.CrossRefGoogle ScholarPubMed
Sabot, Oliver, Cohen, Justin M., Hsiang, Michelle S., et al.Costs and financial feasibility of malaria elimination.” The Lancet 376, no. 9752 (2010): 1604–15.Google Scholar
Sachs, Jeffrey, and Malaney, Pia. “The economic and social burden of malaria.” Nature 415, no. 6872 (2002): 680–5.Google Scholar
Shillcutt, Samuel, Morel, Chantal, Goodman, Catherine, Paul, et al.Cost-effectiveness of malaria diagnostic methods in sub-Saharan Africa in an era of combination therapy.” Bulletin of the World Health Organization 86, no. 2 (2008): 101–10.Google Scholar
Shillcutt, Samuel, Morel, Chantal, Goodman, Catherine, et al.Cost-effectiveness of malaria diagnostic methods in sub-Saharan Africa in an era of combination therapy.” Bulletin of the World Health Organization 86, no. 2 (2008): 101–10.Google Scholar
Smith, David L., Klein, Eili Y., Ellis McKenzie, F., and Laxminarayan, Ramanan. “Prospective strategies to delay the evolution of anti-malarial drug resistance: weighing the uncertainty.” Malaria Journal 9, no. 1 (2010): 217.Google Scholar
Smith, David L., Cohen, Justin M., Chiyaka, Christinah, et al.A sticky situation: the unexpected stability of malaria elimination.” Philosophical Transactions of the Royal Society B: Biological Sciences 368, no. 1623 (2013): 20120145.Google Scholar
Watkins, W. M. and Mosobo, M.Treatment of Plasmodium falciparum malaria with pyrimethamine-sulphadoxine: selective pressure for resistance is a function of long elimination half-life.” Transactions of the Royal Society of Tropical Medicine and Hygiene 87, (1993): 75–8.Google Scholar
White, Michael T., Conteh, Lesong, Cibulskis, Richard, and Ghani, Azra C.. “Costs and cost-effectiveness of malaria control interventions-a systematic review.” Malaria Journal 10, no. 337 (2011): 14752875.Google Scholar
White, N. J.Assessment of the pharmacodynamic properties of antimalarial drugs in vivo.” Antimicrobial Agents and Chemotherapy 41, no. 7 (1997): 1413.CrossRefGoogle ScholarPubMed
White, Nicholas. “Antimalarial drug resistance and combination chemotherapy.” Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 354, no. 1384 (1999): 739–49.CrossRefGoogle ScholarPubMed
Wongsrichanalai, Chansuda, Barcus, Mazie J., Muth, Sinuon, Sutamihardja, Awalludin, and Wernsdorfer, Walther H.. “A review of malaria diagnostic tools: microscopy and rapid diagnostic test (RDT).” The American Journal of Tropical Medicine and Hygiene 77, no. 6 Suppl (2007): 119–27.Google Scholar
World Health Organization. “Insecticide-treated mosquito nets: a WHO position statement” (Geneva: WHO, 2007).Google Scholar
World Health Organization. “World malaria report 2012” (Geneva: WHO, 2012).Google Scholar
World Health Organization. World Malaria Report 2008 Geneva: World Health Organization, 2008).Google Scholar

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