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Case 41 - A 35-Year-Old at 26 Weeks’ Gestation Presents with Fever and Diarrhea after Shopping at a Farmer’s Market

from Section 5 - Antepartum (Infectious Complications)

Published online by Cambridge University Press:  08 April 2025

Peter F. Schnatz
Affiliation:
The Reading Hospital, Pennsylvania
D. Yvette LaCoursiere
Affiliation:
University of California, San Diego
Christopher M. Morosky
Affiliation:
University of Connecticut School of Medicine
Jonathan Schaffir
Affiliation:
The Ohio State University College of Medicine
Vanessa Torbenson
Affiliation:
Mayo Clinic Alix School of Medicine
David Chelmow
Affiliation:
Virginia Commonwealth School of Medicine
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Summary

A 35-year-old gravida 4 para 3 presents with a fever and diarrhea in the setting of exposure to raw and unpasteurized foods. Symptoms are consistent with listeriosis and a local outbreak of Listeria monocytogenes is identified. The patient is managed inpatient with empiric high-dose amoxicillin for 14 days while awaiting blood culture results, along with fetal monitoring and supportive care to prevent dehydration and electrolyte imbalance. L. monocytogenes causes the clinical disease listeriosis and about 16% of cases occur in pregnant women. Increased susceptibility to listeriosis is partly due to reduced T cell immunity. Symptoms can range from asymptomatic to severe disease with neurological symptoms. Transplacental infection can occur with neonatal disease even in the absence of maternal symptoms. Maternal, perinatal, and neonatal morbidity and mortality are high. The best strategy is primary prevention by avoiding high-risk foods such as deli meat and soft cheeses, along with raw and unpasteurized foods. Safe food storage and preparation techniques also have a role in decreasing infection from cross contamination. Individual decision-making and a discussion of risks should guide individual food related decisions.

Type
Chapter
Information
Pregnancy Complications
A Case-Based Approach
, pp. 124 - 127
Publisher: Cambridge University Press
Print publication year: 2025

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References

Committee Opinion No. 614: Management of pregnant women with presumptive exposure to Listeria monocytogenes. Obstet Gynecol. 2014;124:1241–1244.CrossRefGoogle Scholar
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Centers for Disease Control and Prevention (CDC). Vital Signs: Listeria Illnesses, Deaths, and Outbreaks: United States, 2009–2011. MMWR Morb Mortal Wkly Rep. 2013;62 (22):448452. www.ncbi.nlm.nih.gov/pmc/articles/PMC4604984/ (accessed June 14, 2023).Google Scholar
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US Food and Drug Administration/USDA Food Safety and Inspection Agency. Quantitative Assessment of the Relative Risk to Public Health from Food-borne Listeria monocytogenes among Selected Categories of Ready-to-Eat Foods. www.fda.gov/media/124721/download (accessed June 4, 2023).Google Scholar
US Department of Health and Human Services. Food Safety Website. www.foodsafety.gov (accessed July 12, 2023).Google Scholar

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