Book contents
- Practical Psychopharmacology
- Practical Psychopharmacology
- Copyright page
- Dedication
- Contents
- Foreword
- Preface
- Abbreviations
- Part I General Principles
- 1 Core Concepts of Good Psychopharmacology
- 2 Targets of Treatment: Categories versus Dimensions of Psychopathology
- 3 Interpreting and Using the Literature: Integrating Evidence-Based Trials with Real-World Practice
- 4 Placebo and Nocebo Effects
- 5 Tailoring the Fit: Moderators and Mediators of Treatment Outcome
- 6 Complex Regimens and Rationale-Based Combination Drug Therapies
- 7 Laboratory Values and Psychiatric Symptoms: What to Measure, What Not to Measure, and What to Do With The Results
- 8 Pharmacogenetics: When Relevant, When Not
- 9 Cross-tapering and the Logistics of Drug Discontinuation
- 10 Managing Major Adverse Drug Effects: When to Avoid, Switch, or Treat Through
- 11 Novel Drug Therapeutics: Nutraceuticals, Steroids, Probiotics, and Other Dietary Supplements
- 12 Human Diversity and Considerations in Special Populations
- Part II Targets of Pharmacotherapy
- References
- Index
1 - Core Concepts of Good Psychopharmacology
from Part I - General Principles
Published online by Cambridge University Press: 19 October 2021
- Practical Psychopharmacology
- Practical Psychopharmacology
- Copyright page
- Dedication
- Contents
- Foreword
- Preface
- Abbreviations
- Part I General Principles
- 1 Core Concepts of Good Psychopharmacology
- 2 Targets of Treatment: Categories versus Dimensions of Psychopathology
- 3 Interpreting and Using the Literature: Integrating Evidence-Based Trials with Real-World Practice
- 4 Placebo and Nocebo Effects
- 5 Tailoring the Fit: Moderators and Mediators of Treatment Outcome
- 6 Complex Regimens and Rationale-Based Combination Drug Therapies
- 7 Laboratory Values and Psychiatric Symptoms: What to Measure, What Not to Measure, and What to Do With The Results
- 8 Pharmacogenetics: When Relevant, When Not
- 9 Cross-tapering and the Logistics of Drug Discontinuation
- 10 Managing Major Adverse Drug Effects: When to Avoid, Switch, or Treat Through
- 11 Novel Drug Therapeutics: Nutraceuticals, Steroids, Probiotics, and Other Dietary Supplements
- 12 Human Diversity and Considerations in Special Populations
- Part II Targets of Pharmacotherapy
- References
- Index
Summary
When someone takes a medication for depression, anxiety, or any other psychiatric problem, how do they or the prescriber know for certain if they are actually better or worse? And in either instance, whether to credit (or blame) the drug? If depression gets better 4–6 weeks after taking an antidepressant, how confidently should we attribute improvement to the drug rather than to serendipity? What if the patient gets better only after 14–16 weeks – is that too far in time to distinguish a plausible drug effect from spontaneous remission? Or, when can we assume the outcome was still a likely drug effect, given that an adequate trial may take longer in some people than others? If they felt better in just a few days, is that evidence of a placebo effect?
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- Information
- Practical PsychopharmacologyTranslating Findings From Evidence-Based Trials into Real-World Clinical Practice, pp. 3 - 24Publisher: Cambridge University PressPrint publication year: 2021