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35 - Common Electrolyte Disorders (Sodium, Potassium, Calcium, Magnesium)

from Section 7 - Renal Emergencies

Published online by Cambridge University Press:  02 November 2023

Kaushal Shah
Affiliation:
Weill Cornell Medical Center, New York
Jarone Lee
Affiliation:
Massachusetts General Hospital, Boston
Clark G. Owyang
Affiliation:
Weill Cornell Medical Center, New York
Benjamin Christian Renne
Affiliation:
Massachusetts General Hospital, Boston
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Summary

Serum sodium (Na) concentration is mediated by free water intake, circulating levels of antidiuretic hormone (ADH) and renal filtration of sodium. Disorders of potassium, especially hyperkalemia, are the most feared electrolyte disorders due to their ability to cause life-threatening cardiac arrhythmia. Release of calcium stores into the circulation is regulated by extracellular calcium concentration, parathyroid hormone (PTH), vitamin D metabolites and calcitonin. Magnesium is one of the most abundant cations in the body and plays a large role in cardiac contractility as well as nerve conduction.

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Publisher: Cambridge University Press
Print publication year: 2023

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References

al-Ghamdi, SM, Cameron, EC, Sutton, RA. Magnesium deficiency: pathophysiologic and clinical overview. Am J Kidney Dis 1994;24(5):737–52. https://doi.org/10.1016/s0272-6386(12)80667-6CrossRefGoogle ScholarPubMed
Braun, M, Barstow, C, Pyzocha, N, et al. Diagnosis and management of sodium disorders: hyponatremia and hypernatremia. AAFP Guidelines, 2015.Google ScholarPubMed
Bullard, Z, Dattero, J, Zimmerman, LH, et al. In-hospital hypocalcemia. Crit Care Med 2019;47:126. https://doi.org/10.1097/01.ccm.0000551044.21178.02CrossRefGoogle Scholar
Grams, ME, Hoenig, MP, Hoorn, EJ. Evaluation of hypokalemia. JAMA 2021;325(12):12161217. https://doi.org/10.1001/jama.2020.17672CrossRefGoogle ScholarPubMed
Levis, JT. ECG diagnosis: hypokalemia. Perm J 2012;16(2):57.CrossRefGoogle ScholarPubMed
Pepe, J, Colangelo, L, Biamonte, F, et al. Diagnosis and management of hypocalcemia. Endocrine 2020;69(3):485495. https://doi.org/10.1007/s12020-020-02324-2CrossRefGoogle ScholarPubMed
Shepshelovich, D, Leibovitch, C, Klein, A, et al. The syndrome of inappropriate antidiuretic hormone secretion: distribution and characterization according to etiologies. Eur J Int Med 2015;26(10):819824. https://doi.org/10.1016/j.ejim.2015.10.020CrossRefGoogle ScholarPubMed
Shepshelovich, D, Schechter, A, Calvarysky, B, et al. Medication-induced SIADH: distribution and characterization according to medication class. Br J Clin Pharmacol 2017;83(8):18011807. https://doi.org/10.1111/bcp.13256CrossRefGoogle ScholarPubMed
Sood, L, Sterns, RH, Hix, JK, et al. Hypertonic saline and desmopressin: a simple strategy for safe correction of severe hyponatremia. Am J Kidney Dis 2013;61(4):571578; https://doi.org/10.1053/j.ajkd.2012.11.032CrossRefGoogle ScholarPubMed
Spasovski, G, Vanholder, R, Allolio, B, et al. Hyponatraemia Guideline Development Group. Clinical practice guideline on diagnosis and treatment of hyponatraemia. Eur J Endocrinol 2014;170(3):G1G47.CrossRefGoogle ScholarPubMed

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