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Chapter 10 - Traumatic Brain Injury and Psychogenic Nonepileptic Seizures

Published online by Cambridge University Press:  10 August 2021

By
David K. Chen  and
W. Curt LaFrance
Edited by
Marco Mula
Marco Mula
Affiliation:
St George's Hospital Medical School, University of London
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Summary

Psychogenic nonepileptic seizures (PNES) are paroxysms of altered sensory, cognitive, and/or motor manifestations with or without alteration of consciousness that may resemble epileptic seizures, but do not originate from epileptiform brain activity. One framework conceives PNES as arising from a biopsychosocial, multifactorial etiologic model. An unexpectedly high co-occurrence rate of PNES and mild traumatic brain injury (mTBI) has been reported. A causal relationship may be possible in many cases. In applying the biopsychosocial framework, this review discusses how TBI may subserve contributing roles as Predisposing, Precipitating, and Perpetuating factors in the development of PNES.

Keywords

Psychogenic Nonepileptic seizuresTraumatic brain injuryNetwork disorderFunctional connectivityBiopsychosocial modelPredisposing factorsPrecipitating factorsPerpetuating factors
Type
Chapter
Information
Post-traumatic Epilepsy , pp. 140 - 148
Publisher: Cambridge University Press
Print publication year: 2021

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