Skip to main content Accessibility help
×
Hostname: page-component-55f67697df-gmt7q Total loading time: 0 Render date: 2025-05-08T14:58:15.007Z Has data issue: false hasContentIssue false

7 - Renal and Metabolic Aging

from Section 2 - General Health and Illness

Published online by Cambridge University Press:  06 January 2018

Sheila Ryan Barnett
Affiliation:
Harvard University Medical School, Massachusetts
Sara E. Neves
Affiliation:
Beth Israel Deaconess Medical Center, Boston, MA, USA
Get access
Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2018

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Book purchase

Temporarily unavailable

References

Klotz, U. Pharmacokinetics and drug metabolism in the elderly. Drug Metab Rev. 2009; 41(2):6776.CrossRefGoogle ScholarPubMed
Deiner, S, Silverstein, JH. Anesthesia for geriatric patients. Minerva Anestesiol. 2011; 77(2):180189.Google ScholarPubMed
Sharma, A, Mucino, MJ, Ronco, C. Renal functional reserve and renal recovery after acute kidney injury. Nephron Clin Pract. 2014; 127(1-4):94100.CrossRefGoogle ScholarPubMed
Sophie, S. Anaesthesia for the elderly patient. J Pak Med Assoc. 2007; 57(4):196201.Google ScholarPubMed
2014 National Population Projections: summary tables. 2014; Available at: www.census.gov/population/projections/data/national/2014/summarytables.html. (Accessed July 5, 2017).Google Scholar
Tonner, PH, Kampen, J, Scholz, J. Pathophysiological changes in the elderly. Best Pract Res Clin Anaesthesiol. 2003; 17(2):163177.CrossRefGoogle ScholarPubMed
McLachlan, AJ, Bath, S, Naganathan, V, et al. Clinical pharmacology of analgesic medicines in older people: impact of frailty and cognitive impairment. Br J Clin Pharmacol. 2011; 71(3):351364.CrossRefGoogle ScholarPubMed
Grassi, M, Petraccia, L, Mennuni, G, et al. Changes, functional disorders, and diseases in the gastrointestinal tract of elderly. Nutr Hosp. 2011; 26(4):659668.Google ScholarPubMed
Steele, AC, Meechan, JG. Pharmacology and the elderly. Dent Update. 2010; 37(10):666–8, 670–2.CrossRefGoogle ScholarPubMed
Hilmer, SN, McLachlan, AJ, Le Couteur, DG. Clinical pharmacology in the geriatric patient. Fundam Clin Pharmacol. 2007; 21(3):217230.CrossRefGoogle ScholarPubMed
Butler, JM, Begg, EJ. Free drug metabolic clearance in elderly people. Clin Pharmacokinet. 2008; 47(5):297321.CrossRefGoogle ScholarPubMed
Crome, P. Pharmacokinetics in older people. Exp Lung Res. 2005; 31(Suppl 1):8083.Google ScholarPubMed
Turnheim, K. When drug therapy gets old: pharmacokinetics and pharmacodynamics in the elderly. Exp Gerontol. 2003; 38(8):843853.CrossRefGoogle ScholarPubMed
Vuyk, J. Pharmacodynamics in the elderly. Best Pract Res Clin Anaesthesiol. 2003; 17(2):207218.CrossRefGoogle ScholarPubMed
Kazama, T, Ikeda, K, Morita, K, et al. Relation between initial blood distribution volume and propofol induction dose requirement. Anesthesiology. 2001; 94(2):205210.CrossRefGoogle ScholarPubMed
Polasek, TM, Patel, F, Jensen, BP, et al. Predicted metabolic drug clearance with increasing adult age. Br J Clin Pharmacol. 2013; 75(4):10191028.CrossRefGoogle ScholarPubMed
Colloca, G, Santoro, M, Gambassi, G. Age-related physiologic changes and perioperative management of elderly patients. Surg Oncol. 2010; 19(3):124130.CrossRefGoogle ScholarPubMed
Lamb, EJ, O'Riordan, SE, Delaney, MP. Kidney function in older people: pathology, assessment and management. Clin Chim Acta. 2003; 334(1–2):2540.CrossRefGoogle ScholarPubMed
Buemi, M, Nostro, L, Aloisi, C, et al. Kidney aging: from phenotype to genetics. Rejuvenation Res. 2005; 8(2):101109.CrossRefGoogle ScholarPubMed
Giannelli, SV, Patel, KV, Windham, BG, et al. Magnitude of underascertainment of impaired kidney function in older adults with normal serum creatinine. J Am Geriatr Soc. 2007; 55(6):816823.CrossRefGoogle ScholarPubMed
El-Sharkawy, AM, Sahota, O, Maughan, RJ, Lobo, DN. The pathophysiology of fluid and electrolyte balance in the older adult surgical patient. Clin Nutr. 2014; 33(1):613.CrossRefGoogle ScholarPubMed
Allison, SP, Lobo, DN. Fluid and electrolytes in the elderly. Curr Opin Clin Nutr Metab Care. 2004; 7(1):2733.CrossRefGoogle ScholarPubMed
Ferenczi, E, Datta, SS, Chopada, A. Intravenous fluid administration in elderly patients at a London hospital: a two-part audit encompassing ward-based fluid monitoring and prescribing practice by doctors. Int J Surg. 2007; 5(6):408412.CrossRefGoogle Scholar
Luckey, AE, Parsa, CJ. Fluid and electrolytes in the aged. Arch Surg. 2003; 138(10):10551060.CrossRefGoogle ScholarPubMed
Keita, H, Tubach, F, Maalouli, J, Desmonts, JM, Mantz, J. Age-adapted morphine titration produces equivalent analgesia and adverse effects in younger and older patients. Eur J Anaesthesiol. 2008; 25(5):352356.CrossRefGoogle ScholarPubMed
Paolisso, G. Pathophysiology of diabetes in elderly people. Acta Biomed. 2010; 81(Suppl 1):4753.Google ScholarPubMed
Meneilly, GS. Pathophysiology of type 2 diabetes in the elderly. Clin Geriatr Med. 1999; 15(2):239253.CrossRefGoogle ScholarPubMed
Geloneze, B, de Oliveira Mda, S, Vasques, AC, Novaes, FS, Pareja, JC, Tambascia, MA. Impaired incretin secretion and pancreatic dysfunction with older age and diabetes. Metabolism. 2014; 63(7):922929.CrossRefGoogle ScholarPubMed
Nin, V, Chini, CC, Escande, C, Capellini, V, Chini, EN. Deleted in breast cancer 1 (DBC1) protein regulates hepatic gluconeogenesis. J Biol Chem. 2014; 289(9):55185527.CrossRefGoogle ScholarPubMed
Peeters, RP. Thyroid hormones and aging. Hormones (Athens). 2008; 7(1):2835.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×