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Case 8 - Valvular masses

from Section 1 - Cardiac pseudotumors and other challenging diagnoses

Published online by Cambridge University Press:  05 June 2015

Stefan L. Zimmerma
Affiliation:
Johns Hopkins University School of Medicine
Stefan L. Zimmerman
Affiliation:
Johns Hopkins Medical Centre
Elliot K. Fishman
Affiliation:
Johns Hopkins Medical Centre
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Summary

Imaging description

Valvular masses can be challenging when encountered on cardiac CT or MRI. Echocardiography is the test of choice for evaluation of the valves; however, in some patients, CT or MRI may be requested due to lack of adequate imaging windows or need to evaluate for associated complications. Vegetations in the setting of infective endocarditis are more common than valvular tumors, are mobile during the cardiac cycle, low attenuation on CT (Figure 8.1), and low signal intensity on T1- and T2-weighted MRI. They are associated with valvular thickening or other sequelae of infectious endocarditis such as valvular regurgitation, perforation (Figure 8.1), fistulas between cardiac chambers, paravalvular abscesses, and pseudoaneurysms. Primary tumors of the valve are rare. Of these, the most commonly encountered valvular tumor is a papillary fibroelastoma which is commonly round with an irregular, frond-like surface. It will be low in attenuation on CT images (Figure 8.2), similar to the valve tissue, and will have intermediate T1 and high T2 signal intensity on MRI with homogenous delayed enhancement (Figure 8.3). Papillary fibroelastomas are usually mobile on a stalk, moving with the valve leaflets through the cardiac cycle. Involvement of the aortic and mitral valve is more common than the tricuspid and pulmonic valve.

Importance

Although rare, valvular masses are important to recognize at cardiac imaging due to the fact that they pose a risk of distal embolization. In patients with infective endocarditis, neurologic complications develop in 20–40%. Although benign, the treatment of choice for valvular tumors is surgical resection to avoid these complications. Antibiotic therapy may be used to treat vegetations; however, in complicated cases, such as those with fistulas or abscesses, surgical valve replacement may be necessary.

Typical clinical scenario

Valvular masses may be encountered incidentally or may be referred to advanced imaging after discovery at echocardiography. Coronary CT angiography may be used to preoperatively evaluate the coronary arteries in patients who are planned for valve replacement.

Type
Chapter
Information
Pearls and Pitfalls in Cardiovascular Imaging
Pseudolesions, Artifacts, and Other Difficult Diagnoses
, pp. 26 - 29
Publisher: Cambridge University Press
Print publication year: 2015

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References

1. Bennett, C. J., Maleszewski, J. J., Araoz, P. A.. CT and MR imaging of the aortic valve: radiologic-pathologic correlation. Radiographics 2012; 32: 1399–420.CrossRefGoogle Scholar
2. Mylonakis, E., Calderwood, S. B.. Infective endocarditis in adults. N Engl J Med 2001; 345: 1318–30.CrossRefGoogle ScholarPubMed
3. Feuchtner, G. M., Stolzmann, P., Dichtl, W., et al. Multislice computed tomography in infective endocarditis: comparison with transesophageal echocardiography and intraoperative findings. J Am Coll Cardiol 2009; 53: 436–44.CrossRefGoogle ScholarPubMed

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