Published online by Cambridge University Press: 02 March 2020
Since the very early years (1969–1978) of human IVF, Patrick Steptoe and Robert Edwards were utilizing a range of pharmaceutical agents for ovarian stimulation, ovulation induction, and luteal phase support (e.g., urinary gonadotrophins, chorionic gonadotrophin, clomiphene citrate, progesterone). However, in spite of their efforts with these agents, their breakthrough pregnancy following ovarian stimulation was sadly an ectopic.
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