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7 - Infectious disease and modern epidemiology

Published online by Cambridge University Press:  24 November 2009

Gerald Esch
Affiliation:
Wake Forest University, North Carolina
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Summary

Life is as tedious as a twice-told tale, Vexing the dull ear of a drowsy man;

King John, William Shakespeare (1564–1616)

Ross, Bailey, Hairston, Bradley, Michel, McDonald, are all names that will be recognized immediately by any epidemiologist/modeler working on eukaryotic parasites. Almost all of these people studied and published prior to 1971, beginning with Sir Ronald Ross who, I am sorry to say, rather feebly attempted to predict the prevalence of malaria in mathematical terms. Most investigators in this area would agree that the seminal publications for the modern epidemiology of helminth parasites were those of Crofton (1971a, b). His efforts were truly the ‘seeds’ for what followed. Harry Crofton, most unfortunately, died very young, not long in fact after publishing his two papers in 1971. I have often wondered what would have followed had he lived a longer life.

Early in my career, I had the pleasure of spending almost an entire year (1971–72) at Imperial College in London with Desmond Smyth, who was trying to teach me the intricacies of in vitro culture. He succeeded, but in doing so, I also learned that this sort of research is tedious, very expensive, and, frankly (for me, at least), terribly boring. It was about that time that I turned my complete attention to ecological pursuits.

Type
Chapter
Information
Parasites and Infectious Disease
Discovery by Serendipity and Otherwise
, pp. 203 - 218
Publisher: Cambridge University Press
Print publication year: 2007

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References

Anderson, R. M. and May, R. M.. 1978. Regulation and stability of host-parasite population interactions: I. Regulatory processes. Journal of Animal Ecology 47: 219–247.CrossRefGoogle Scholar
Anderson, R. M. and May, R. M.. 1979. Population biology of infectious diseases. Part I. Nature 280: 361–367.CrossRefGoogle ScholarPubMed
Crofton, H. D. 1971a. A quantitative approach to parasitism. Parasitology 62: 646–661.CrossRefGoogle Scholar
Crofton, H. D. 1971b. A model for host-parasite relationships. Parasitology 63: 343–364.CrossRefGoogle Scholar
McDonald, G. 1965. The dynamics of helminth infections with special reference to schistosomes. Transactions of the Royal Society of Tropical Medicine and Hygiene 59: 489–506.CrossRefGoogle Scholar
May, R. M. and Anderson, R. M.. 1978. Regulation and stability of host-parasite interactions: II. Destabilizing processes. Journal of Animal Ecology 47: 249–267.CrossRefGoogle Scholar
May, R. M. and Anderson, R. M.. 1979. Population biology of infectious diseases. Part II. Nature 280: 455–454.CrossRefGoogle ScholarPubMed

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