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Chapter 21 - Luteinizing Hormone Supplementation during Ovarian Stimulation

from Section 4 - Non-conventional Forms Used during Ovarian Stimulation

Published online by Cambridge University Press:  14 April 2022

By
Ioannis E. Messinis ,
Christina I. Messini ,
George Anifandis  and
Alexandros Daponte
Edited by
Mohamed Aboulghar  and
Botros Rizk
Mohamed Aboulghar
Affiliation:
University of Cairo IVF Centre
Botros Rizk
Affiliation:
University of South Alabama
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Summary

Folliculogenesis in humans is a long process. It has become clear that there are two main time points in follicular development, the “initial recruitment” that takes place at the stage of primordial follicles and the “cyclic recruitment” at the stage of small antral follicles [1]. In humans, the initial recruitment is gonadotropin independent, while cyclic recruitment is entirely dependent on the action of both follicle-stimulating hormone (FSH) and luteinizing hormone (LH) [2]. Locally produced substances affect the action of gonadotrophins on follicle maturation. The balanced effect of FSH and LH in the normal menstrual cycle ensures the selection of a single follicle.

Type
Chapter
Information
Ovarian Stimulation , pp. 199 - 207
Publisher: Cambridge University Press
Print publication year: 2022

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