Skip to main content Accessibility help
×
Hostname: page-component-78c5997874-t5tsf Total loading time: 0 Render date: 2024-11-05T08:45:37.018Z Has data issue: false hasContentIssue false

6 - Six Patterns of Human Genomic Variation

Published online by Cambridge University Press:  14 December 2022

Rasmus Grønfeldt Winther
Affiliation:
University of California, Santa Cruz
Get access

Summary

In pursuit of more nuanced answers about ourselves and each other, we must shift from metrics and models to interpretation and applications of genomic analyses, both in scientific and medical contexts, and in broader culture and politics. Accordingly, this chapter presents six general empirical patterns of human genomic variation. The patterns emerge from many data points, layered through measures and metrics such as heterozygosity and Euclidean genetic distance, statistical modeling machinery, such as variance partitioning protocols and Bayesian clustering algorithms, and theoretical concepts, such as population and genetic variation. Because the six patterns form an indelible, complex mix of genomic data, statistical methods, and evolutionary genetic theory, I call them neither facts nor data, nor empirical results nor states of affairs. They are also neither models nor methodologies. They are much too complex and unique for such simple and straightforward denominations.

Type
Chapter
Information
Our Genes
A Philosophical Perspective on Human Evolutionary Genomics
, pp. 164 - 189
Publisher: Cambridge University Press
Print publication year: 2022

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×