Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-23T08:51:14.467Z Has data issue: false hasContentIssue false

Chapter 49 - Systemic Lupus Erythematosus and Antiphospholipid Antibody Syndrome in Pregnancy

from Section 8 - Connective Tissue Disorders in Pregnancy

Published online by Cambridge University Press:  23 February 2023

By
Oseme Etomi  and
Catherine Nelson-Piercy
Edited by
Amira El-Messidi  and
Alan D. Cameron
Amira El-Messidi
Affiliation:
McGill University, Montréal
Alan D. Cameron
Affiliation:
University of Glasgow
Get access

Summary

A 28-year-old nulligravida is referred by her primary care provider to your high-risk obstetrics clinic for preconception counseling for known systemic lupus erythematosus (SLE).

Keywords

Preconception counselingSystemic lupus erythematosus (SLE)Antiphospholipid antibody syndrome (APLAS)Catastrophic APLASComorbiditiesImmune featuresPharmacology, treatment, hydroxychloroquine, heparinsPreeclampsia, low-dose aspirin, vitamin DDrug-induced lupusPerinatal risks, complications, maternal-fetal morbidity, adverse outcomeInvestigations, prenatalPreconception counsellingFlare, antenatalNeonatal lupus syndromeNeonatal cutaneous lupus syndromeCongenital heart blockContraception
Type
Chapter
Information
OSCEs in Obstetrics and Maternal-Fetal Medicine
An Evidence-Based Approach
 , pp. 619 - 634
Publisher: Cambridge University Press
Print publication year: 2023

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Suggested Readings

Andreoli, L, Bertsias, GK, Agmon-Levin, N, et al. EULAR recommendations for women’s health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with systemic lupus erythematosus and/or antiphospholipid syndrome. Ann Rheum Dis. 2017;76(3):476–485.CrossRefGoogle ScholarPubMed
Do, SC, Druzin, ML. Systemic lupus erythematosus in pregnancy: high risk, high reward. Curr Opin Obstet Gynecol. 2019;31(2):120–126.CrossRefGoogle ScholarPubMed
Flint, J, Panchal, S, Hurrell, A, et al. BSR and BHPR guideline on prescribing drugs in pregnancy and breastfeeding-Part I: standard and biologic disease modifying anti-rheumatic drugs and corticosteroids. Rheumatology (Oxford). 2016;55(9):1693–1697.CrossRefGoogle ScholarPubMed
Giles, I, Yee, CS, Gordon, C. Stratifying management of rheumatic disease for pregnancy and breastfeeding. Nat Rev Rheumatol. 2019;15(7):391–402.Google Scholar
Knight, CL, Nelson-Piercy, C. Management of systemic lupus erythematosus during pregnancy: challenges and solutions. Open Access Rheumatol. 2017;9:37–53.Google Scholar
Lazzaroni, MG, Dall’Ara, F, Fredi, M, et al. A comprehensive review of the clinical approach to pregnancy and systemic lupus erythematosus. J Autoimmun. 2016;74:106–117.CrossRefGoogle ScholarPubMed
Nahal, SK, Selmi, C, Gershwin, ME. Safety issues and recommendations for successful pregnancy outcome in systemic lupus erythematosus. J Autoimmun. 2018;93:16–23.Google Scholar
Nelson-Piercy’s Handbook of Obstetric Medicine, 6th ed. London: Taylor and Francis; 2020.Google Scholar
Petri, M. Pregnancy and systemic lupus erythematosus. Best Pract Res Clin Obstet Gynaecol. 2020;64:24–30.CrossRefGoogle ScholarPubMed
Sammaritano, LR, Bermas, BL, Chakravarty, EE, et al. 2020 American College of Rheumatology guideline for the management of reproductive health in rheumatic and musculoskeletal diseases. Arthritis Rheumatol. 2020;72(4):529–556.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×