Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-78c5997874-j824f Total loading time: 0 Render date: 2024-11-05T17:09:03.406Z Has data issue: false hasContentIssue false

Chapter 59 - Cytomegalovirus Infection in Pregnancy

from Section 11 - Infectious Conditions in Pregnancy

Published online by Cambridge University Press:  23 February 2023

By
Amira El-Messidi  and
Eva Suarthana
Edited by
Amira El-Messidi  and
Alan D. Cameron
Amira El-Messidi
Affiliation:
McGill University, Montréal
Alan D. Cameron
Affiliation:
University of Glasgow
Get access

Summary

A healthy 23-year-old G2P1 presents for prenatal care at 12+0 weeks’ gestation by dating ultrasound. Her last pregnancy was cared for by your colleague, who is currently away. Pregnancy was uncomplicated, and she had a spontaneous vaginal delivery at term. You learn from the antenatal notes that the patient had a flu-like illness in early pregnancy; investigations were unremarkable, and symptoms resolved with supportive care. She tells you her healthy two-year-old son has been attending daycare since six months of age and is meeting his developmental milestones.

Keywords

Cytomegalovirus, pregnancyRisk factorsLifestyle measures, preventionFetal diagnosis, sonography, short-term morbidity, long-term morbidity, congenital infectionInvestigationsDiagnosis, maternal serology, avidity testing, polymerase chain reaction (PCR)CounselingMaternal therapyUniversal screening testSensitivity, specificity, relative risk, calculation, area under the curve
Type
Chapter
Information
OSCEs in Obstetrics and Maternal-Fetal Medicine
An Evidence-Based Approach
 , pp. 763 - 773
Publisher: Cambridge University Press
Print publication year: 2023

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Suggested Readings

Bartlett, AW, Hamilton, ST, Shand, AW, et al. Fetal therapies for cytomegalovirus: what we tell prospective parents. Prenat Diagn. 2020;1–12.CrossRefGoogle Scholar
Boucoiran, I, Yudin, M, Poliquin, V, et al. Guideline No. 420: cytomegalovirus infection in pregnancy. J Obstet Gynaecol Can. 2021;43(7):893–908. [Correction in J Obstet Gynaecol Can. 2021 Oct 11]Google Scholar
Bonita, R, Beaglehole, R, Kjellström, T. Basic Epidemiology. 2nd ed. Geneva: WHO; 2016.Google Scholar
Gaur, P, Ffrench-Constant, S, Kachramanoglou, C, et al. Is it not time for international guidelines to combat congenital cytomegalovirus infection? a review of central nervous system manifestations. Clin Radiol. 2020;75(8): 644.Google Scholar
Kagan, KO, Hamprecht, K. Cytomegalovirus infection in pregnancy. Arch Gynecol Obstet. 2017;296(1):15–26.Google Scholar
Khalil, A, Heath, P, Jones, C, et al. Congenital cytomegalovirus infection: update on treatment: Scientific Impact Paper No. 56. BJOG. 2018;125(1):e1–e11.Google Scholar
Lazzarotto, T, Blázquez-Gamero, D, Delforge, ML, et al. Congenital cytomegalovirus infection: a narrative review of the issues in screening and management from a panel of European experts. Front Pediatr. 2020;8:13.Google Scholar
Leruez-Ville, M, Ville, Y. Fetal cytomegalovirus infection. Best Pract Res Clin Obstetr Gynaecol 2017;38:97–107.CrossRefGoogle ScholarPubMed
Rawlinson, WD, Boppana, SB, Fowler, KB, et al. Congenital cytomegalovirus infection in pregnancy and the neonate: consensus recommendations for prevention, diagnosis, and therapy. Lancet Infect Dis. 2017;17(6):e177–e188.CrossRefGoogle ScholarPubMed
Society for Maternal-Fetal Medicine (SMFM), Hughes, BL, Gyamfi-Bannerman, C. Diagnosis and antenatal management of congenital cytomegalovirus infection. Am J Obstet Gynecol. 2016;214(6):B5–B11.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×