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Chapter 18 - Hepatic Conditions

Published online by Cambridge University Press:  26 January 2024

By
Arash Motamed ,
Thang Tran  and
Mohamed H. Eloustaz
Edited by
David R. Gambling ,
M. Joanne Douglas  and
Grace Lim
David R. Gambling
Affiliation:
University of California, San Diego
M. Joanne Douglas
Affiliation:
University of British Columbia, Vancouver
Grace Lim
Affiliation:
University of Pittsburgh
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Summary

The hormonal changes of pregnancy induce changes in the liver’s anatomy, physiology, and function. These can lead to diagnostic difficulties if liver disease is present during pregnancy. For example, spider nevi and palmar erythema are signs of liver disease but exist in some healthy pregnant women. However, liver size is unchanged in pregnancy, so the presence of hepatomegaly suggests liver disease. Even though the proportion of cardiac output flowing to the liver is reduced by 35%, hepatic blood flow remains unchanged from the nonpregnant state because of the overall increase in blood volume and cardiac output associated with pregnancy.

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Information
Obstetric Anesthesia and Uncommon Disorders , pp. 290 - 304
Publisher: Cambridge University Press
Print publication year: 2024

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