Skip to main content Accessibility help
×
Hostname: page-component-586b7cd67f-2brh9 Total loading time: 0 Render date: 2024-11-26T14:02:59.079Z Has data issue: false hasContentIssue false

33 - Transfusion,anaphylactic and drug reactions

from Section 6 - Anaesthetic Emergencies. Section Editor: Anthony Addei

Published online by Cambridge University Press:  05 November 2012

Edwin Chandraharan
Affiliation:
St George’s University of London
Sabaratnam Arulkumaran
Affiliation:
St George’s University of London
Get access

Summary

This chapter describes immune reactions occurring during transfusion of blood or blood products and adverse drug reactions. Coagulopathy, hypothermia, citrate toxicity hyperkalaemia and transfusion-related acute lung injury (TRALI) are some of adverse effects from massive blood transfusion. Anaphylaxis in obstetrics may be life threatening not only for the pregnant mother but also for the fetus. If anaphylaxis occurs at the time of a caesarean section, then the diagnosis may be difficult to make. There might be some confusion identifying the offending agent because several drugs are administered at the same time. Most reactions occur either due to an exaggeration of the predicted pharmacological effect or unpredictably and unrelated to a drug's main pharmacological action. Cyclizine, oxytocin, carboprost and atracurium are examples of drug that have an adverse effect when administered in the obstetric setting.
Type
Chapter
Information
Obstetric and Intrapartum Emergencies
A Practical Guide to Management
, pp. 227 - 232
Publisher: Cambridge University Press
Print publication year: 2012

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×