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Chapter 16 - Musculoskeletal Disorders and Pain in Parkinson’s Disease

Published online by Cambridge University Press:  05 March 2022

By
Ovidiu-Alexandru Bajenaru
Edited by
Néstor Gálvez-Jiménez ,
Amos D. Korczyn  and
Ramón Lugo-Sanchez
Néstor Gálvez-Jiménez
Affiliation:
Florida International University
Amos D. Korczyn
Affiliation:
Tel-Aviv University
Ramón Lugo-Sanchez
Affiliation:
Cleveland Clinic
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Summary

Musculoskeletal disorders and pain in Parkinson’s disease (PD) are two complex clinically and pathophysiologically distinct problems, but a high degree of overlap exists between the pathogenesis and understanding of these two types of clinical manifestations. Although not commonly recognized as such these non-motor symptoms are quite frequent, impacting patients’ qualify of life. . Early clinical observations [1] have noticed that both musculoskeletal disorders and pain related to these appear even in the prodromal phase, but also during definite PD manifestation, mainly by different algic syndromes determined by so-called fibromyalgia (fibrositis, tendinitis, myalgia), shoulder pain, cervicobrachialgia, ischialgia, lower back pain, and arthralgia. These probably appear indirectly as a component of PD, and seem to be significantly improved by the administration of levodopa. In PD patients with motor fluctuations, musculoskeletal pain tends to occur more often when parkinsonian disability is maximal and less frequently when disability is minimal [2].

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Chapter
Information
Non-motor Parkinson's Disease , pp. 178 - 186
Publisher: Cambridge University Press
Print publication year: 2022

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