This chapter first traces the history of Bible in North America, and then the issue of publishing of the Scripture. The strongly Protestant cast of American history is indicated no better than in the intense personal application to Scripture undertaken by countless individuals in every generation from the early seventeenth century to the present. Americans also have sustained an enormous rate of bible publication and an even more astonishing appetite for literature about the Bible. The Scripture has been a vital element in American popular life, and has also provided powerful themes for Americans to define themselves politically, both as a people and as a nation. The chapter discusses the experiences of two minority groups in North America, Jews and the African Americans, for whom the Bible has been central. It ends with discussions on the Biblical scholarship, and the history of the Scripture in Canada.