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Chapter 8 - Neuron Models

from Section 1 - Basic and Computational Neuroscience

Published online by Cambridge University Press:  04 January 2024

By
Kumaresh Krishnan
Edited by
Farhana Akter ,
Nigel Emptage ,
Florian Engert  and
Mitchel S. Berger
Farhana Akter
Affiliation:
Harvard University, Massachusetts
Nigel Emptage
Affiliation:
University of Oxford
Florian Engert
Affiliation:
Harvard University, Massachusetts
Mitchel S. Berger
Affiliation:
University of California, San Francisco
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Summary

Viewing the neuron as an electrical system gives an easy handle into modeling the generation and transmission of action potentials. In the simplest version of this framework, the entire neuron can be viewed as having a single membrane potential. Models built on this assumption are termed “single-compartment” models. A more detailed assessment of the spatial variation in membrane potential gives rise to “multi-compartment” models. We now look at the basic electrical properties of spiking neurons that are essential to most models

Type
Chapter
Information
Neuroscience for Neurosurgeons , pp. 134 - 145
Publisher: Cambridge University Press
Print publication year: 2024

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References

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Gerstner, W, Kistler, WM. Spiking neuron Models: Single Neurons, Populations, Plasticity. Cambridge University Press, 2002.Google Scholar
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Lapicque, L. Recherches quantitatives sur l’excitation e´lectrique des nerfs traite´e comme une polarization. J Physiol Pathol Gen 1907;9:620–35.Google Scholar

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