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Chapter 13 - Prognostication in Sepsis-Associated Encephalopathy

from Part I - Disease-Specific Prognostication

Published online by Cambridge University Press:  14 November 2024

By
William Roth ,
Marie-Carmelle Elie-Turenne  and
Carolina B. Maciel
Edited by
David M. Greer  and
Neha S. Dangayach
David M. Greer
Affiliation:
Boston University School of Medicine and Boston Medical Center
Neha S. Dangayach
Affiliation:
Icahn School of Medicine at Mount Sinai and Mount Sinai Health System
Get access

Summary

Sepsis, a life-threatening dysregulated host response to infection, represents the leading cause of death among adults in US hospitals and remains one of the most prevalent causes of death in children worldwide.[1,2] Every year in the United States, 1 in 1,000 people will become septic, and over half of these will require intensive care.[3,4] The estimated 5-year mortality related to sepsis approaches 80%.[5] Following the widespread implementation of sepsis guidelines, 3-year absolute mortality has significantly decreased by 20%.[6] The increased survivorship of sepsis patients has prompted the investigation of long-term outcomes including cognitive, psychiatric, functional, and quality-of-life sequelae.

Type
Chapter
Information
Neuroprognostication in Critical Care , pp. 193 - 205
Publisher: Cambridge University Press
Print publication year: 2024

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