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Chapter 14 - EEG Monitoring in Neonates and Children Undergoing Extracorporeal Membrane Oxygenation

from Part IV - Practice of Neuromonitoring: Cardiac Intensive Care Unit

Published online by Cambridge University Press:  08 September 2022

Cecil D. Hahn
Affiliation:
The Hospital for Sick Children, University of Toronto
Courtney J. Wusthoff
Affiliation:
Lucile Packard Children’s Hospital, Stanford University
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Summary

Extracorporeal membrane oxygenation (ECMO) is a temporary cardiopulmonary support for neonates and children with potentially reversible cardiopulmonary disorders. Patients requiring ECMO support are at risk for brain injury due to pre-ECMO medical conditions, ECMO cannula placement in the carotid artery and internal jugular vessels, and complications arising during ECMO. Acute brain injury may result in acute symptomatic seizures. Clinical and electrographic seizures are common in neonates and children undergoing ECMO. At the same time, the majority of seizures during ECMO are subclinical, and can only be diagnosed through continuous EEG monitoring. Thus, recent consensus statements have recommended increasing use of continuous EEG monitoring (cEEG) during ECMO in neonates and children. This chapter reviews the available data regarding seizure incidence, risk factors, and outcomes in neonates and children requiring ECMO support.

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Publisher: Cambridge University Press
Print publication year: 2022

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References

Cengiz, P, Seidel, K, Rycus, PT, Brogan, TV, Roberts, JS. Central nervous system complications during pediatric extracorporeal life support: incidence and risk factors. Crit Care Med. 2005;33(12):2817–24.CrossRefGoogle ScholarPubMed
Short, BL. The effect of extracorporeal life support on the brain: a focus on ECMO. Semin Perinatol. 2005;29(1):4550.CrossRefGoogle Scholar
Karimova, A, Brown, K, Ridout, D, et al. Neonatal extracorporeal membrane oxygenation: practice patterns and predictors of outcome in the UK. Arch Dis Child Fetal Neonatal Ed. 2009;94(2):F129–32.Google Scholar
Hervey-Jumper, SL, Annich, GM, Yancon, AR, et al. Neurological complications of extracorporeal membrane oxygenation in children. J Neurosurg Pediatr. 2011;7(4):338–44.CrossRefGoogle ScholarPubMed
Chrysostomou, C, Maul, T, Callahan, PM, et al. Neurodevelopmental outcomes after pediatric cardiac ECMO support. Front Pediatr. 2013;1:47.CrossRefGoogle ScholarPubMed
de Mol, AC, Liem, KD, van Heijst, AF. Cerebral aspects of neonatal extracorporeal membrane oxygenation: a review. Neonatology. 2013;104(2):95103.CrossRefGoogle ScholarPubMed
Mehta, A, Ibsen, LM. Neurologic complications and neurodevelopmental outcome with extracorporeal life support. World J Crit Care Med. 2013;2(4):40–7.CrossRefGoogle ScholarPubMed
Piantino, JA, Wainwright, MS,. Grimason, M, et al. Nonconvulsive seizures are common in children treated with extracorporeal cardiac life support. Pediatr Crit Care Med. 2013;14(6):601–9.CrossRefGoogle ScholarPubMed
Polito, A, Barrett, CS, Wypij, D, et al. Neurologic complications in neonates supported with extracorporeal membrane oxygenation. An analysis of ELSO registry data. Intensive Care Med. 2013;39(9):1594601.CrossRefGoogle ScholarPubMed
Beghi, E, Carpio, A, Forsgren, L., et al. Recommendation for a definition of acute symptomatic seizure. Epilepsia. 2010;51(4):671–5.CrossRefGoogle ScholarPubMed
Shellhaas, RA, Chang, T, Tsuchida, T, et al. The American Clinical Neurophysiology Society’s guideline on continuous electroencephalography monitoring in neonates. J Clin Neurophysiol. 2011;28(6):611–17.Google Scholar
Herman, ST, Abend, NS, Bleck, TP, et al., and E. E. G. T. F. o. t. A. C. N. S. Critical Care Continuous. Consensus statement on continuous EEG in critically ill adults and children, part I: indications. J Clin Neurophysiol. 2015a;32(2):8795.CrossRefGoogle ScholarPubMed
Herman, ST, Abend, NS, Bleck, TP, et al. Consensus statement on continuous EEG in critically ill adults and children, part II: personnel, technical specifications, and clinical practice. J Clin Neurophysiol. 2015b;32(2):96108.CrossRefGoogle ScholarPubMed
Bembea, MM, Felling, R, Anton, B. Salorio, CF, Johnston, MV. Neuromonitoring during extracorporeal membrane oxygenation: a systematic review of the literature. Pediatr Crit Care Med. 2015;16(6):558–64.CrossRefGoogle ScholarPubMed
Lin, JJ, Banwell, BL, Berg, RA, et al. Electrographic seizures in children and neonates undergoing extracorporeal membrane oxygenation. Pediatr Crit Care Med. 2017;18(3):249–57.CrossRefGoogle ScholarPubMed
Okochi, S, Shakoor, A, Barton, S, et al. Prevalence of seizures in pediatric extracorporeal membrane oxygenation patients as measured by continuous electroencephalography. Pediatr Crit Care Med. 2018;19(12):1162–7.CrossRefGoogle ScholarPubMed
Yuliati, A, Federman, M, Rao, LM, et al. Prevalence of seizures and risk factors for mortality in a continuous cohort of pediatric extracorporeal membrane oxygenation patients. Pediatr Crit Care Med. 2020;21(11):949–58.CrossRefGoogle Scholar
Sansevere, AJ, DiBacco, ML, Akhondi-Asl, A, et al. EEG features of brain injury during extracorporeal membrane oxygenation in children. Neurology. 2020;95(1):e1372e1380.CrossRefGoogle ScholarPubMed
Horan, M, Azzopardi, D, Edwards, AD, Firmin, RK, Field, D. Lack of influence of mild hypothermia on amplitude integrated-electroencephalography in neonates receiving extracorporeal membrane oxygenation. Early Hum Dev. 2007;83(2):6975.CrossRefGoogle ScholarPubMed
Hahn, JS, Vaucher, Y, Bejar, R, Coen, RW. Electroencephalographic and neuroimaging findings in neonates undergoing extracorporeal membrane oxygenation. Neuropediatrics. 1993;24(1):1924.Google Scholar
Streletz, LJ, Bej, MD, Graziani, LJ, et al. Utility of serial EEGs in neonates during extracorporeal membrane oxygenation. Pediatr Neurol. 1992;8(3):190–6.CrossRefGoogle ScholarPubMed
Haines, NM, Rycus, PT, Zwischenberger, JB, Bartlett, RH, Undar, A. Extracorporeal Life Support Registry Report 2008: neonatal and pediatric cardiac cases. ASAIO J. 2009;55(1):111–16.CrossRefGoogle ScholarPubMed
Campbell, LR, Bunyapen, C, Gangarosa, ME, Cohen, M, KantoJr., WP. Significance of seizures associated with extracorporeal membrane oxygenation. J Pediatr. 1991;119(5):789–92.CrossRefGoogle ScholarPubMed
Nasr, D. M, Rabinstein, AA. Neurologic complications of extracorporeal membrane oxygenation. J Clin Neurol. 2015;11(4):383–9.CrossRefGoogle ScholarPubMed
Abend, NS, Topjian, AA, Williams, S. Could EEG monitoring in critically ill children be a cost-effective neuroprotective strategy? J Clin Neurophysiol. 2015a;32(6):486–94.CrossRefGoogle ScholarPubMed
Abend, NS, Topjian, AA, Williams, S. How much does it cost to identify a critically ill child experiencing electrographic seizures? J Clin Neurophysiol. 2015b;32(3):257–64.Google Scholar
Bennett, CC, Johnson, A, Field, DJ. A comparison of clinical variables that predict adverse outcome in term infants with severe respiratory failure randomised to a policy of extracorporeal membrane oxygenation or to conventional neonatal intensive care. J Perinat Med. 2002;30(3):225–30.CrossRefGoogle ScholarPubMed
Parish, AP, Bunyapen, C, Cohen, MJ, Garrison, T, Bhatia, J. Seizures as a predictor of long-term neurodevelopmental outcome in survivors of neonatal extracorporeal membrane oxygenation (ECMO). J Child Neurol. 2004;19(12):930–4.CrossRefGoogle ScholarPubMed
Fitzgerald, MP, Donnelly, M, Vala, L, Allen-Napoli, L, Abend, NS. Collodion remover can degrade plastic-containing medical devices commonly used in the intensive care unit. Neurodiagn J. 2019;59(3):163–8.CrossRefGoogle ScholarPubMed
Matsumoto, JH, McArthur, DL, Szeliga, CW, et al. Conductive plastic electrodes reduce EEG artifact during pediatric ECMO therapy. J Clin Neurophysiol. 2016;33(5):426–30.CrossRefGoogle ScholarPubMed
Abend, NS, Dlugos, DJ, Zhu, X, Schwartz, ES. Utility of CT-compatible EEG electrodes in critically ill children. Pediatr Radiol. 2015;45(5):714–18.CrossRefGoogle ScholarPubMed
Tsuchida, TN, Wusthoff, CJ, Shellhaas, RA, et al.; C. American Clinical Neurophysiology Society Critical Care Monitoring. American Clinical Neurophysiology Society standardized EEG terminology and categorization for the description of continuous EEG monitoring in neonates: report of the American Clinical Neurophysiology Society critical care monitoring committee. J Clin Neurophysiol. 2013;30(2):161–73.CrossRefGoogle ScholarPubMed
Hirsch, LJ, LaRoche, SM, Gaspard, N, et al. American Clinical Neurophysiology Society’s Standardized Critical Care EEG Terminology: 2012 version. J Clin Neurophysiol. 2013;30(1):127.CrossRefGoogle ScholarPubMed

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