The Importance of Movement Disorders in Inborn Errors of Metabolism

Chapter 2 - The Importance of Movement Disorders in Inborn Errors of Metabolism

from Section I - General Principles and a Phenomenology-Based Approach to Movement Disorders and Inherited Metabolic Disorders

Published online by Cambridge University Press: 24 September 2020

Angeles García-Cazorla

Edited by

Darius Ebrahimi-Fakhari and

Phillip L. Pearl

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Darius Ebrahimi-Fakhari: Affiliation:
Harvard Medical School
Phillip L. Pearl: Affiliation:
Harvard Medical School

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Summary

The study of abnormal movements has been an important topic in neurology since over a century ago. In fact, movement disorders are a rapidly growing subspecialty that receives contributions from different disciplines including adult neurology, child neurology, neurosurgery, psychiatry, and physical medicine and rehabilitation. The main focus is on normal and abnormal functioning of the motor systems and on possibilities to treat motor dysfunction. The traditional approach to study and treat movement disorders has been largely based on the analysis of the clinical phenomenology that results from the interaction of a number of brain regions that provide motor control under different functional states. Therefore the development of anatomical and physiological studies of the neural circuitry of motor systems, together with the precise description of corresponding clinical signs, has encouraged the study of this broad topic during the last decades. Brain imaging, neurophysiology, and basic research studies in animal models have provided an increasing amount of knowledge.

Type: Chapter
Information: Movement Disorders and Inherited Metabolic Disorders
Recognition, Understanding, Improving Outcomes
, pp. 15 - 25

DOI: https://doi.org/10.1017/9781108556767 [Opens in a new window]

Publisher: Cambridge University Press

Print publication year: 2020

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