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Chapter 8 - Cognitive Impairment and Endocrine Conditions

Published online by Cambridge University Press:  14 October 2021

By
Anne M. Doherty  and
Seán F. Dinneen
Edited by
Anne M. Doherty ,
Aoife M. Egan  and
Sean Dinneen
Anne M. Doherty
Affiliation:
University College Dublin
Aoife M. Egan
Affiliation:
Division of Endocrinology and Metabolism, Mayo Clinic, Minnesota, USA
Sean Dinneen
Affiliation:
School of Medicine, National University of Ireland, Galway
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Summary

Cognitive impairment or dementia is increasing in prevalence worldwide and may be an unrecognised and early complication of a number of endocrine conditions, including diabetes mellitus and thyroid disease. In addition, these conditions may be predisposing factors towards developing dementia. In this chapter, we will discuss these issues with reference to diabetes in particular, being the endocrine disorder with the strongest association with cognitive impairment. Identifying cognitive impairments among people with endocrine disorders is important, as is identifying endocrine conditions in people living with dementia, as this may require adjustment of therapeutic targets and of treatment. There are particular challenges in certain clinical groups, including depressive pseudodementia, behavioural and psychological symptoms of dementia, frailty and mild cognitive impairment. Targets for glycaemic control may need to be relaxed in this group of patients, and this is supported by international best practice guidelines.

Keywords

dementiaendocrinologydiabetesmental healthmild cognitive impairment
Type
Chapter
Information
Mental Health, Diabetes and Endocrinology , pp. 81 - 94
Publisher: Cambridge University Press
Print publication year: 2021

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