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Chapter 36 - Molecular Biology and Physiology of Erectile Function and Dysfunction

from Section 5 - Medical and Surgical Management of Issues of Male Health

Published online by Cambridge University Press:  06 December 2023

By
James L. Liu ,
Arthur L. Burnett  and
Amin S. Herati
Edited by
Douglas T. Carrell ,
Alexander W. Pastuszak  and
James M. Hotaling
Douglas T. Carrell
Affiliation:
Utah Center for Reproductive Medicine
Alexander W. Pastuszak
Affiliation:
University of Utah
James M. Hotaling
Affiliation:
Utah Center for Reproductive Medicine
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Summary

Male erectile dysfunction is a common condition that can significantly impact quality of life and interpersonal relationships. It is strongly associated with aging, comorbid conditions, poor lifestyle, and adverse cardiovascular health. Deficits in psychologic, neurologic, vascular, and endocrine function can all lead to erectile dysfunction. The aim of this chapter is to review the molecular biology required for erectile function as well as delve into the clinical pathophysiology that leads to erectile dysfunction.

Keywords

erectile functionnitric oxidemolecular mediatorsvascular dysfunctionneurologic deficitspsychogenic
Type
Chapter
Information
Men's Reproductive and Sexual Health Throughout the Lifespan
An Integrated Approach to Fertility, Sexual Function, and Vitality
 , pp. 289 - 294
Publisher: Cambridge University Press
Print publication year: 2023

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