Skip to main content Accessibility help
×
Hostname: page-component-cd9895bd7-jkksz Total loading time: 0 Render date: 2024-12-26T16:42:36.887Z Has data issue: false hasContentIssue false

6 - Why Failures Occur in the Safe Management of Medications

Published online by Cambridge University Press:  09 April 2021

Alan Merry
Affiliation:
University of Auckland
Joyce Wahr
Affiliation:
University of Minnesota
Get access

Summary

The process of medication management in anesthesia is both complicated (numerous steps) and complex, in that it requires continual adaptation to a continually changing environment. In addition, medication safety depends on systemic factors, some of which involve processes far from the clinical interface. The system in which medications are managed is complex, if only because humans are a key part of this system. The processes of human cognition are particularly complex, and include knowledge, evidence, information, wisdom and expertise. These processes are explored in some detail, including a discussion of short term and long-term memory. Each practitioner responds to an internally developed mental model of the current situation, which may differ considerable from that of other team members. An understanding of complexity and human cognition may often provide an explanation for failure in healthcare: such an understanding provides a foundation for our overall pursuit of medication safety.

Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2021

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Merry, AF, Anderson, BJ. Medication errors: time for a national audit? Paediatr Anaesth. 2011;21(11):116970.Google Scholar
Llewellyn, RL, Gordon, PC, Reed, AR. Drug administration errors – time for national action. S Afr Med J. 2011;101(5):31920.Google Scholar
Merry, AF, Webster, CS. Medication error in New Zealand – time to act. N Z Med J. 2008;121(1272):69.Google Scholar
Orser, BA. Medication safety in anesthetic practice: first do no harm. Can J Anaesth. 2000;47(11):10512.Google Scholar
Eichhorn, J. APSF hosts medication safety conference: consensus group defines challenges and opportunities for improved practice. APSF Newsletter. 2010;25(1):17. Accessed January 3, 2020. https://www.apsf.org/article/apsf-hosts-medication-safety-conference/Google Scholar
Clutton-Brock, J. Two cases of poisoning by contamination of nitrous oxide with higher oxides of nitrogen during anaesthesia. Br J Anaesth. 1967;39(5):38892.CrossRefGoogle ScholarPubMed
Obituary. Professor John Clutton Brock, MA, MB, BChir, DA. Bristol Med Chir J. 1987;102(1):267.Google Scholar
Taylor, MB, Christian, KG, Patel, N, Churchwell, KB. Methemoglobinemia: toxicity of inhaled nitric oxide therapy. Pediatr Crit Care Med. 2001;2(1):99101.Google Scholar
Lorenz, E. Does the flap of a butterfly's wings in Brazil set off a Tornado in Texas? Paper presented at: American Association for the Advancement of Science, 139th Meeting; December 29, 1972; Cambridge, MA. Accessed January 16, 2020. http://eaps4.mit.edu/research/Lorenz/Butterfly_1972.pdfGoogle Scholar
Moppett, IK, Shorrock, ST. Working out wrong-side blocks. Anaesthesia. 2017;27:15.Google Scholar
Glouberman, S, Zimmerman, B. Complicated and Complex Systems: What Would Successful Reform of Medicare Look Like? Commission on the Future of Health Care in Canada; 2002. Discussion Paper No. 8. Accessed January 2, 2020. https://www.alnap.org/system/files/content/resource/files/main/complicatedandcomplexsystems-zimmermanreport-medicare-reform.pdfGoogle Scholar
Gawande, A. The Checklist Manifesto. New York, NY: Metropolitan Books; 2009.Google Scholar
Braithwaite, J, Churruca, K, Ellis, LA, et al. Complexity Science in Healthcare – Aspirations, Approaches, Applications and Accomplishments: A White Paper. Australian Institute of Health Innovation; 2017. Accessed July 17, 2020. https://www.mq.edu.au/__data/assets/pdf_file/0003/680754/Braithwaite-2017-Complexity-Science-in-Healthcare-A-White-Paper.pdfGoogle Scholar
Perrow, C. Normal Accidents: Living with High Risk Technologies. 2nd ed. Princeton, NJ: Princeton University Press; 1999.Google Scholar
Webster, CS, Merry, AF, Larsson, L, McGrath, KA, Weller, J. The frequency and nature of drug administration error during anaesthesia. Anaesth Intensive Care. 2001;29(5):494500.CrossRefGoogle ScholarPubMed
Fraind, DB, Slagle, JM, Tubbesing, VA, Hughes, SA, Weinger, MB. Reengineering intravenous drug and fluid administration processes in the operating room: step one: task analysis of existing processes. Anesthesiology. 2002;97(1):13947.Google Scholar
Wahr, JA, Merry, AF. Medication errors in the perioperative setting. Curr Anesthesiol Rep. 2017;7(3):32029.Google Scholar
Merry, AF, Webster, CS, Hannam, J, et al. Multimodal system designed to reduce errors in recording and administration of drugs in anaesthesia: prospective randomised clinical evaluation. BMJ. 2011;343:d5543.Google Scholar
Norman, D. Things That Make Us Smart: Defending Human Attributes in the Age of the Machine. Reading, MA: Perseus; 1993.Google Scholar
Craig, DB, Longmuir, J. Implementation of Canadian Standards Association Z168.3-M 1980 Anaesthetic Gas Machine Standard: the Manitoba experience. Can Anaesth Soc J. 1980;27(5):5049.Google Scholar
Reason, J. Human Error. New York, NY: Cambridge University Press; 1990.Google Scholar
Lipshitz, R, Ben Shaul, O. Schemata and Mental Models in Recognition-Primed Decision Making. Naturalistic Decision Making. Mahwah, NJ: Lawrence Earlbaum Associates; 1997:293303.Google Scholar
Nakarada-Kordic, I, Weller, JM, et al. Assessing the similarity of mental models of operating room team members and implications for patient safety: a prospective, replicated study. BMC Med Educ. 2016;16(1):229.Google Scholar
Rudolph, JW, Simon, R, Dufresne, RL, Raemer, DB. There's no such thing as “nonjudgmental” debriefing: a theory and method for debriefing with good judgment. Simul Healthc. 2006;1(1):4955.Google Scholar
Sackett, DL, Rosenberg, WM, Gray, JA, Haynes, RB, Richardson, WS. Evidence based medicine: what it is and what it isn't. Br Med J. 1996;312(7023):712.Google Scholar
Merry, AF, Davies, JM, Maltby, JR. Qualitative research in health care. Br J Anaesth. 2000;84(5):5525.Google Scholar
Merry, AF, Webster, CS, Holland, RL, et al. Clinical tolerability of perioperative tenoxicam in 1001 patients – a prospective, controlled, double-blind, multi-centre study. Pain. 2004;111(3):31322.CrossRefGoogle ScholarPubMed
Zeleney, M. Management support systems: towards integrated knowledge management. HSM. 1987;7(1):5970.Google Scholar
Ackoff, RL. From data to wisdom. J Appl Syst Anal. 1989;16:39.Google Scholar
Dammann, O. Data, information, evidence, and knowledge: a proposal for health informatics and data science. Online J Public Health Inform. 2018;10(3):e224.Google ScholarPubMed
Wahr, JA, Abernathy, JH 3rd, Lazarra, EH, et al. Medication safety in the operating room: literature and expert-based recommendations. Br J Anaesth. 2017;118(1):3243.Google Scholar
Bawden, D, Robinson, L. The dark side of information: overload, anxiety and other paradoxes and pathologies. J Inf Sci. 2009;35(2):18091.Google Scholar
Loadsman, JA. Dilemmas in biomedical research publication: are we losing the plot? Curr Opin Anaesthesiol. 2012;25(6):7305.Google Scholar
Moore, RA, Derry, S, McQuay, HJ. Fraud or flawed: adverse impact of fabricated or poor quality research. Anaesthesia. 2010;65(4):32730.Google Scholar
Merry, AF. Ethics, industry, and outcomes. Semin Cardiothorac Vasc Anesth. 2008;12(1):711.Google Scholar
Shafer, SL. Tattered threads. Anesth Analg. 2009;108(5):13613.Google Scholar
Loadsman, JA, McCulloch, TJ. Widening the search for suspect data – is the flood of retractions about to become a tsunami? Anaesthesia. 2017;72(8):9315.Google Scholar
Carlisle, JB. Data fabrication and other reasons for non-random sampling in 5087 randomised, controlled trials in anaesthetic and general medical journals. Anaesthesia. 2017;72(8):94452.CrossRefGoogle ScholarPubMed
Kharasch, ED, Houle, TT. Seeking and reporting apparent research misconduct: errors and integrity. Anaesthesia. 2018;73(1):1256.CrossRefGoogle ScholarPubMed
Carlisle, JB. Seeking and reporting apparent research misconduct: errors and integrity – a reply. Anaesthesia. 2018;73(1):1268.Google Scholar
Runciman, B, Merry, A, Walton, M. Safety and Ethics in Healthcare: A Guide to Getting It Right. Aldershot, UK: Ashgate Publishing; 2007.Google Scholar
Sidebotham, D, Merry, AF, Legget, M, eds. Practical Perioperative Transoesophageal Echocardiography. London, UK: Butterworth-Heinemann; 2003.Google Scholar
Rayner, K, White, SJ, Johnson, RL, Liversedge, SP. Raeding wrods with jubmled lettres: there is a cost. Psychol Sci. 2006;17(3):1923.Google Scholar
Rupp, SM. Color-coding of syringes may not enhance safety. Reg Anesth Pain Med. 2005;30(6):58990.Google Scholar
Grissinger, M. Color-coded syringes for anesthesia drugs – use with care. P T. 2012;37(4):199201.Google Scholar
Christie, W, Hill, MR. Standardized colour coding for syringe drug labels: a national study. Anaesthesia. 2002;57:7938.Google Scholar
International Organization for Standardization. Anaesthetic and respiratory equipment – user-applied labels for syringes containing drugs used during anaesthesia – colours, design and performance. ISO 26825:2008. Accessed January 20, 2020. https://www.iso.org/standard/43811.htmlGoogle Scholar
Haslam, GM, Sims, C, McIndoe, AK, Saunders, J, Lovell, AT. High latent drug administration error rates associated with the introduction of the international colour coding syringe labelling system. Eur J Anaesthesiol. 2006;23(2):1658.CrossRefGoogle ScholarPubMed
Wickboldt, N, Balzer, F, Goncerut, J, et al. A survey of standardised drug syringe label use in European anaesthesiology departments. Eur J Anaesthesiol. 2012;29(9):44651.CrossRefGoogle ScholarPubMed
Evley, R, Russell, J, Mathew, D, et al. Confirming the drugs administered during anaesthesia: a feasibility study in the pilot National Health Service sites, UK. Br J Anaesth. 2010;105(3):28996.Google Scholar
Jelacic, S, Bowdle, A, Nair, BG, et al. A system for anesthesia drug administration using barcode technology: the Codonics Safe Label System and Smart Anesthesia Manager. Anesth Analg. 2015;121(2):41021.Google Scholar
Merry, AF, Webster, CS, Mathew, DJ. A new, safety-oriented, integrated drug administration and automated anesthesia record system. Anesth Analg. 2001;93(2):38590.Google Scholar
Inturrisi, CE, Verebely, K. The levels of methadone in the plasma in methadone maintenance. Clin Pharmacol Ther. 1972;13(5):6337.CrossRefGoogle ScholarPubMed
Loftus, EF. Memory distortion and false memory creation. Bull Am Acad Psychiatry Law. 1996;24(3):28195.Google Scholar
Loftus, EF. Planting misinformation in the human mind: a 30-year investigation of the malleability of memory. Learn Mem. 2005;12(4):3616.Google Scholar
Loftus, EF. 25 Years of eyewitness science … finally pays off. Perspect Psychol Sci. 2013;8(5):5567.CrossRefGoogle Scholar
Veselis, RA. Memory formation during anaesthesia: plausibility of a neurophysiological basis. Br J Anaesth. 2015;115(suppl 1):i13i19.Google Scholar
Klein, G. Sources of Power: How People Make Decisions. Cambridge, MA: MIT Press; 1999.Google Scholar
Simon, HA. Rational choice and the structure of the environment. Psychol Rev. 1956;63(2):12938.Google Scholar
Endsley, M. The role of situational awareness in naturalistic decision making. In: Zsambok, CE, Klein, G, eds. Naturalistic Decision Making. Mahwah, NJ: Lawrence Erlbaum Associates; 1997:26983.Google Scholar
Gladwell, M. Blink. The Power of Thinking Without Thinking. New York, NY: Little, Brown and Company; 2005.Google Scholar
Rotella, JA, Yeoh, M. Taming the zebra: unravelling the barriers to diagnosing aortic dissection. Emerg Med Australas. 2018;30(1):11921.Google Scholar
Kahneman, D. Thinking, Fast and Slow. London: Penguin Books; 2011.Google Scholar
Thaler, R, Sunstein, C. Nudge: Improving Decisions about Health, Wealth and Happiness. New Haven, CT: Yale University Press; 2008.Google Scholar
Stiegler, MP, Neelankavil, JP, Canales, C, Dhillon, A. Cognitive errors detected in anaesthesiology: a literature review and pilot study. Br J Anaesth. 2012;108(2):22935.Google Scholar
Stiegler, MP, Tung, A. Cognitive processes in anesthesiology decision making. Anesthesiology. 2014;120(1):20417.Google Scholar
Caplan, RA, Posner, KL, Cheney, FW. Effect of outcome on physician judgments of appropriateness of care. JAMA. 1991;265(15):195760.Google Scholar
Merry, AF, Brookbanks, W. Merry and McCall Smith's Errors, Medicine and the Law. 2nd ed. Cambridge, UK: Cambridge University Press; 2017.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×