When Wollstonecraft’s Vindication of the Rights of Woman (1792) was first published, it was categorised in Joseph Johnson’s Analytical Review as a work of political economy. The introduction asks what this term meant for Wollstonecraft and her contemporaries, and argues that it was used to understand the nature and operation of modern commercial society, as well as the potential for its reformation. Wollstonecraft’s relation to this project is explored, both through a survey of her engagement with Adam Smith and through her lived experience as an unmarried, often indebted woman in a society organised around possession of property. Wollstonecraft is presented as a writer engaging throughout her career as a critic of the connected material, economic, moral, psychological, and social conditions of modern commercial contemporaneity, and as anticipating the opposition to political economy of later Romantic writers.