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Chapter 15 - Management of Twin-Reversed Arterial Perfusion (TRAP) Sequence

Published online by Cambridge University Press:  11 October 2022

Leanne Bricker
Affiliation:
Corniche Hospital, Abu Dhabi
Julian N. Robinson
Affiliation:
Brigham & Women's Hospital, Boston
Baskaran Thilaganathan
Affiliation:
St George's Hospital Medical School, University of London
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Summary

Twin reversed arterial perfusion sequence (TRAP) is a rare complication of monochorionic twins consisting of complete retrograde blood perfusion with consequent developmental disruption and malformation of one twin (acardiac twin), blood bypass of the placenta and subsequent hemodynamic overload in the otherwise normally developed twin (pump twin). Recent studies have identified a higher incidence than historically reported and identification in early pregnancy is crucial to establish opportune diagnosis and management. If not detected, the survival rate of the pump twin is only 50 – 60%, as heart failure, fetal hydrops and intrauterine death may develop, as well as miscarriage or preterm delivery may occur. As a result of increasing awareness and early diagnosis, treatment options have shifted from the second to the first trimester in recent years, although optimal timing and mode of intervention is still controversial. In this chapter the incidence, pathophysiology and clinical presentation of TRAP sequence will be discussed, as well as different therapeutic options will be addressed.

Type
Chapter
Information
Management of Multiple Pregnancies
A Practical Guide
, pp. 157 - 167
Publisher: Cambridge University Press
Print publication year: 2022

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References

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