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1.05 - Approach to Depressed or Suicidal Schizophrenia Spectrum Patients

from Part I - Treatment Strategies

Published online by Cambridge University Press:  19 October 2021

Michael Cummings
Affiliation:
University of California, Los Angeles
Stephen Stahl
Affiliation:
University of California, San Diego
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Summary

Negative symptoms and cognitive deficits are major barriers to employment, stable interpersonal relationships, and independent living for persons afflicted with schizophrenia in the community [1]. Negative symptoms, such as blunting of affect, impaired behavioral initiation, decreased motivation, ambivalence, and social withdrawal, interact on a continuum with illness features such as impaired executive functions, decreased verbal fluency, and emotional dyscontrol [2, 3]. Moreover, deficits in emotional control coupled with deficits in impulse control place the schizophrenic individual at elevated risk for suicide. The overall suicide rate in schizophrenia has been estimated to be circa 10%, with suicide being a primary factor involved in shortening the expected life span of schizophrenic patients [4]. Thus, negative symptoms, dysphoric mood states, and suicidality should be considered major treatment targets among complex treatment-resistant patients with schizophrenia.

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Publisher: Cambridge University Press
Print publication year: 2021

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