Hieradoumian tombstones – very unusually for Greek-language epitaphs – typically give the precise date of death in the format year, month, and day, and age at death is also very often specified. As a result, we have a large body of data for analyzing demographic patterns in the region. This chapter analyzes Hieradoumian patterns of seasonal mortality, broken down by sex and age. The results show both similarities and differences with other comparable datasets from other parts of the Greco-Roman Mediterranean. Infants and young children are heavily under-represented in the funerary record, as are (to a lesser extent) women. Since votive inscriptions are also often precisely dated, it is likewise possible to gain some sense of dominant seasonal patterns of religious activity in Roman Hieradoumia. The large number of dated epitaphs from the second-century AD allows us to trace the impact of the Antonine Plague in western Asia Minor; the chapter concludes with a brief discussion of the pathogens which may have shaped ‘normal’ seasonal mortality patterns in the region.