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Chapter 16 - Diseases of the Gallbladder in Infancy, Childhood, and Adolescence

from Section II - Cholestatic Liver Disease

Published online by Cambridge University Press:  19 January 2021

By
Frank W. DiPaola  and
James E. Heubi
Edited by
Frederick J. Suchy ,
Ronald J. Sokol  and
William F. Balistreri
Edited in association with
Jorge A. Bezerra ,
Cara L. Mack  and
Benjamin L. Shneider
Frederick J. Suchy
Affiliation:
University of Colorado, Children’s Hospital Colorado, Aurora
Ronald J. Sokol
Affiliation:
University of Colorado, Children’s Hospital Colorado, Aurora
William F. Balistreri
Affiliation:
Cincinnati Children’s Hospital Medical Center, Cincinnati
Jorge A. Bezerra
Affiliation:
Cincinnati Children’s Hospital Medical Center, Cincinnati
Cara L. Mack
Affiliation:
University of Colorado, Children’s Hospital Colorado, Aurora
Benjamin L. Shneider
Affiliation:
Texas Children’s Hospital, Houston
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Summary

The hepatic rudiment appears at approximately day 18 of gestation in the human embryo. By day 25 it can be recognized as an endodermal diverticulum, which projects into the mesenchymal septum transversum. By day 30 the hepatic diverticulum enlarges and divides into the pars hepatica, cranially, and the pars cystica, caudally. The pars hepatica forms parenchymal liver components; the pars cystica differentiates into the gallbladder and cystic ducts (Figure 16.1). The gallbladder primordium is a solid structure that later in development becomes cystic, as found in the adult [1].

Type
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Information
Liver Disease in Children , pp. 255 - 272
Publisher: Cambridge University Press
Print publication year: 2021

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