The Quaestiones de secretis mulierum of MS Erfurt-Gotha, Universitäts- und Forschungsbibliothek, Dep. Erf., CA 4º 299, ascribed to John Buridan and recently edited for the first time, are an incomplete set of questions on Pseudo-Albert the Great’s De secretis mulierum. The text contains an extensive treatment of the topic of human generation, with a particular focus on male and female roles in reproduction. This essay retraces Buridan’s view on the generative aspects of female physiology as it emerges in his commentary on Pseudo-Albert’s text. By analyzing this unexplored feature of Buridan’s thought, the essay aims to contribute to the growing research on the biological aspects of Buridan’s natural philosophy.