Cultural knowledge is a fundamental part of participating in intercultural communication. Our knowledge of the world – such as history, current issues, belief systems, and values – helps us navigate both the surface-level meaning of language and its cultural significance. Cultural knowledge allows us to participate in practices in social/cultural groups (e.g., knowing how to participate in the educational system or attending prayers). Without adequate or appropriate knowledge of the context, the message of our interlocutors remains incomplete, even if we comprehend the lexicon, grammar, or pragmatics accurately. This chapter explores different ways to organize knowledge that we need to learn for successful intercultural communication and how we develop this knowledge (i.e., sources of knowledge). At the end of the chapter, key concepts pertaining to cultural knowledge are connected to an intercultural communication-oriented pedagogy, with sample language-teaching activities.