This chapter examines cultural transitions, people on the move across the globe who embody a wide range of complex experiences. They include people whose journeys are brief and those who must find permanent new homes, those who are welcomed by the host communities, and those who encounter serious challenges. In other words, people take diverse cultural paths; yet, in spite of their diversity, these journeys also share common characteristics: the need to recognize, and possibly adapt to, new situations, people, beliefs, practices, and ways of communicating. This chapter examines the process of cultural transitions, the change from one’s old self to an intercultural one. It also reviews various models of cultural adaptation, including how individuals move through culture shock to adjust and adapt to new cultural contexts. It also provides suggestions for managing the adaptation process, including measures people can take before, during, and after departure.