This chapter explores how late ancient institutions ordered the knowledge and ways of knowing that were associated with one of the central artefacts of the Christian community: its collection of sacred writings. I spotlight Origen, who was affiliated with a number of such institutions over his lifetime in Alexandria and later in Caesarea Maritima. I will examine how his philosophical schools gave shape and style to his exegetical project. I will also briefly reflect on the other institution with which he was affiliated: the church in Caesarea, where he was ordained as a priest. In a number of ways, I argue, philosophical schools left their imprint on Origen’s scriptural exegesis.