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Chapter 16 - Neuropsychology of Insular Epilepsy

from Section 3 - Noninvasive Investigation of Insular Epilepsy

Published online by Cambridge University Press:  09 June 2022

By
Olivier Boucher ,
Sallie Baxendale ,
Alain Bouthillier  and
Dang Khoa Nguyen
Edited by
Dang Nguyen ,
Jean Isnard  and
Philippe Kahane
Dang Nguyen
Affiliation:
Université de Montréal
Jean Isnard
Affiliation:
Claude Bernard University Lyon
Philippe Kahane
Affiliation:
Grenoble-Alpes University Hospital
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Summary

Epilepsy surgery patients played a pioneering role in our early understanding of the insula in Penfield’s stimulation studies. Following the advent of functional imaging, epilepsy patients are once again helping us understand the role of this critical structure in human behavior. The insular cortex is involved in a wide range of complex human functions, including auditory processing, language function, attention, emotional processing, social cognition, and decision-making. In this chapter, we review this literature and report new data on the postoperative neuropsychological function of a series of 31 patients who have undergone partial or complete insular resections at the Centre Hospitalier de l’Université de Montréal (CHUM). Standard neuropsychological assessments reveal few cognitive impairments specific to insular epilepsy or its surgery. Specialized assessments are required to fully assess the impact of insular resection on socio-emotional processing and behavioral features of executive function that can be compromised following surgery.

Keywords

neuropsychologycognitive functionsemotional processingsocial cognitiondecision-making
Type
Chapter
Information
Insular Epilepsies , pp. 194 - 202
Publisher: Cambridge University Press
Print publication year: 2022

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