Book contents
- Insular Epilepsies
- Insular Epilepsies
- Copyright page
- Contents
- Contributors
- Foreword
- Chapter 1 A Brief History of Insular Cortex Epilepsy
- Section 1 The Human Insula from an Epileptological Standpoint
- Section 2 The Spectrum of Epilepsies Involving the Insula
- Section 3 Noninvasive Investigation of Insular Epilepsy
- Section 4 Invasive Investigation of Insular Epilepsy
- Section 5 Surgical Management of Insular Epilepsy
- Chapter 22 Insular Epilepsy Surgery: Surgical Techniques and Experience of Various Centers
- Chapter 23 Stereoelectroencephalography (SEEG)–Guided Radiofrequency Thermocoagulation (RFTC) of Insular Epileptic Foci
- Chapter 24 Neurostimulation for the Treatment of Insular Epilepsy
- Chapter 25 Laser Interstitial Thermal Therapy (LITT) for Insular Epilepsy
- Epilogue
- Index
- References
Chapter 25 - Laser Interstitial Thermal Therapy (LITT) for Insular Epilepsy
from Section 5 - Surgical Management of Insular Epilepsy
Published online by Cambridge University Press: 09 June 2022
- Insular Epilepsies
- Insular Epilepsies
- Copyright page
- Contents
- Contributors
- Foreword
- Chapter 1 A Brief History of Insular Cortex Epilepsy
- Section 1 The Human Insula from an Epileptological Standpoint
- Section 2 The Spectrum of Epilepsies Involving the Insula
- Section 3 Noninvasive Investigation of Insular Epilepsy
- Section 4 Invasive Investigation of Insular Epilepsy
- Section 5 Surgical Management of Insular Epilepsy
- Chapter 22 Insular Epilepsy Surgery: Surgical Techniques and Experience of Various Centers
- Chapter 23 Stereoelectroencephalography (SEEG)–Guided Radiofrequency Thermocoagulation (RFTC) of Insular Epileptic Foci
- Chapter 24 Neurostimulation for the Treatment of Insular Epilepsy
- Chapter 25 Laser Interstitial Thermal Therapy (LITT) for Insular Epilepsy
- Epilogue
- Index
- References
Summary
Compared to surgery, LITT provides minimal disruption of the brain matter, less post-operative pain and shorter length of stay. LITT has enabled a more minimalist approach to deep-seated targets such as the insula. Increasing utilization of stereoelectroencephalography has allowed for better identification of seizure onset involving the insular cortex and subsequent ablation, including many patients with prior surgeries involving the frontal, parietal, and temporal lobes. The insula serves as an ideal target for LITT, given the deep location and surrounding anatomic structures. There are limited studies on the efficacy of LITT in adults with lesional or non-lesional insular epilepsy. Retrospective LITT studies as well as comparisons with open surgical resection in the pediatric population have, however, shown good comparative efficacy while also demonstrating minimal, often transient, post-operative complications.
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- Insular Epilepsies , pp. 287 - 298Publisher: Cambridge University PressPrint publication year: 2022