from Section 3 - Laboratory Diagnosis of Male Infertility
Published online by Cambridge University Press: 08 July 2023
The evolutionary branch from early primates to human beings dates back about 400 000 years (personal communication, Dr Lee Silver, Princeton University), and in that time, man has endured an “ice age.” In more recent history, man’s interest in cellular responses to freezing temperatures has been primarily concerned with his defense against it. The first cells discovered for the microscopic assessment of changes were sperm by van Leeuwenhoek in 1677, and in 1827, Karl Ernst von Baer later discovered the egg [1]. However, it was a very different and difficult concept for the public to grasp that human life can start with two microscopic gametes and that these cells can be frozen and survive thawing [2].
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