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from Drugs: An A–Z Guide
Published online by Cambridge University Press: 15 January 2025
Ramipril is an ACE-I; ACE-Is have a beneficial role in all grades of heart failure, usually combined with a beta blocker and diuretics. Potassium-sparing diuretics (e.g. spironolactone) should be discontinued before starting an ACE-I because of the risk of hyperkalaemia. However, low-dose spironolactone may also be beneficial in severe heart failure, and, when used together with an ACE-I, serum potassium needs to be monitored closely.
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