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8 - Puberty and depression

Published online by Cambridge University Press:  22 September 2009

By
Adrian Angold ,
Carol Worthman  and
E. Jane Costello
Edited by
Chris Hayward
Adrian Angold
Affiliation:
Associate Professor of Psychiatry and Behavioral Sciences, Duke University Medical Center
Carol Worthman
Affiliation:
Samuel Candler Dobbs Professor of Anthropology, Emory University
E. Jane Costello
Affiliation:
Professor of Medical Psychology, Duke University Medical Center
Chris Hayward
Affiliation:
Stanford University, California
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Summary

In this chapter we will examine evidence concerning the emergence of an excess of unipolar depression in females during adolescence. We will also present new data from the Great Smoky Mountains Study (GSMS) in support of an approach that combines consideration of both the endocrinology of puberty and the effects of stress on depression.

The phenomenon to be explained

Numerous adult studies from around the world have documented that women have 1.5 to 3 times more current and lifetime unipolar depression than men (Bebbington, et al., 1981; Bland, Newman, and Orn, 1988a; Bland, Newman, and Orn, 1988b; Blazer, et al., 1994; Canino, et al., 1987; Cheng, 1989; Hwu, Yeh, and Chang, 1989; Kessler, et al., 1994; Kessler, et al., 1993; Lee, Han, and Choi, 1987; Weissman, et al., 1993; Weissman, et al., 1996; Weissman and Klerman, 1977; Wells, et al., 1989; Wittchen, et al., 1992). In later life (after age 55), the female excess of depressions probably diminishes; mostly on account of falling rates in women (Bebbington, 1996; Bebbington, et al., 1998; Jorm, 1987).

Retrospective data from adults suggested that the female excess did not appear until adolescence (Burke, et al., 1990; Kessler, et al., 1993), and the child and adolescent epidemiological literature agrees that rates of unipolar depression in prepubertal girls are not higher than those in prepubertal boys (Anderson, et al., 1987; Angold, Costello, and Worthman, 1998; Angold, Costello, and Worthman, 1999; Angold and Rutter, 1992; Bird, et al.

Type
Chapter
Information
Gender Differences at Puberty , pp. 137 - 164
Publisher: Cambridge University Press
Print publication year: 2003

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References

American Psychiatric Association (1994). Diagnostic and statistical manual of mental disorders, fourth edition (DSM-IV). Washington, DC: American Psychiatric Press
Anderson, J. C., Williams, S., McGee, R., and Silva, P. A. (1987). DSM-III disorders in preadolescent children: prevalence in a large sample from the general population. Archives of General Psychiatry, 44, 69–77CrossRefGoogle Scholar
Angold, A., and Rutter, M. (1992). The effects of age and pubertal status on depression in a large clinical sample. Development and Psychopathology, 4, 5–28CrossRefGoogle Scholar
Angold, A., Costello, E. J., and Worthman, C. M. (1998). Puberty and depression: the roles of age, pubertal status, and pubertal timing. Psychological Medicine, 28, 51–61CrossRefGoogle ScholarPubMed
Angold, A., Costello, E. J., and Worthman, C. M. (1999). Pubertal changes in hormone levels and depression in girls. Psychological Medicine, 29, 1043–1053CrossRefGoogle ScholarPubMed
Angold, A., Erkanli, A., Costello, E. J., and Rutter, M. (1996). Precision, reliability and accuracy in the dating of symptom onsets in child and adolescent psychopathology. Journal of Child Psychology and Psychiatry, 37, 657–664CrossRefGoogle ScholarPubMed
Angold, A., Prendergast, M., Cox, A., Harrington, R., Simonoff, E., and Rutter, M. (1995). The Child and Adolescent Psychiatric Assessment (CAPA). Psychological Medicine, 25, 739–753CrossRefGoogle Scholar
Apter, D. (1980). Serum steroids and pituitary hormones in female puberty: a partly longitudinal study. Clinical Endocrinology, 12, 107–120CrossRefGoogle ScholarPubMed
Bebbington, P. (1996). The origins of sex differences in depressive disorder: bridging the gap. International Review of Psychiatry, 8, 295–332CrossRefGoogle Scholar
Bebbington, P. E., Dunn, G., Jenkins, R., Lewis, G., Brugha, T., Farrell, M., and Meltzer, H. (1998). The influence of age and sex on the prevalence of depressive conditions: report from the National Survey of Psychiatric Morbidity. Psychological Medicine, 28, 9–10CrossRefGoogle ScholarPubMed
Bebbington, P. E., Hurry, J., Tennant, C., Sturt, E., and Wing, J. K. (1981). Epidemiology of mental disorders in Camberwell. Psychological Medicine, 11, 561–579CrossRefGoogle ScholarPubMed
Bedcarras, P. M. G., Ayuso, S., Escobar, M. E., Bergada, C., and Campo, S. (1998). Characterization of serum SHBG isoforms in prepubertal and pubertal girls. Clinical Endocrinology, 49, 603–608CrossRefGoogle Scholar
Bird, H. R., Canino, G., Rubio-Stipec, M., Gould, M. S., Ribera, J., Sesman, M., Woodbury, M., Huertas-Goldman, S., Pagan, A., Sanchez-Lacay, A., and Moscoso, M. (1988). Estimates of the prevalence of childhood maladjustment in a community survey in Puerto Rico: the use of combined measures. Archives of General Psychiatry, 45, 1120–1126CrossRefGoogle Scholar
Bland, R. C., Newman, S. C., and Orn, H. (1988a). Lifetime prevalence of psychiatric disorders in Edmonton. Acta Psychiatrica Scandinavica, 77, 24–32CrossRefGoogle Scholar
Bland, R. C., Newman, S. C., and Orn, H. (1988b). Period prevalence of psychiatric disorders in Edmonton. Acta Psychiatrica Scandinavica, 77, 33–42CrossRefGoogle Scholar
Blazer, D. G., Kessler, R. C., McGonagle, K. A., and Swartz, M. S. (1994). The prevalence and distribution of major depression in a national community sample: the National Comorbidity Survey. American Journal of Psychiatry, 151, 979–986Google Scholar
Brooks-Gunn, J., and Warren, M. P. (1989). Biological and social contributions to negative affect in young adolescent girls. Child Development, 60, 40–55CrossRefGoogle ScholarPubMed
Burke, K. C., Burke, J. D., Regier, D. A., and Rae, D. S. (1990). Age at onset of selected mental disorders in five community populations. Archives of General Psychiatry, 47, 511–518CrossRefGoogle ScholarPubMed
Burr, I. M., Sizonenko, P. C., Kaplan, S. L., and Grumbach, M. M. (1970). Hormonal changes in puberty. 1. Correlations of serum luteinizing hormone and follicle-stimulating hormone with stages of puberty, testicular size and bone age in normal boys. Pediatric Research, 4, 25–35CrossRefGoogle Scholar
Cairney, J. (1998). Gender differences in the prevalence of depression among Canadian adolescents. Canadian Journal of Public Health, 89, 181–182Google ScholarPubMed
Cairns, R. B., and Cairns, B. D. (1994). Lifelines and risks: pathways of youth in our time, 1st edn. Cambridge: Cambridge University Press
Canino, G. J., Bird, H. R., Shrout, P. E., Rubio-Stipec, M., Bravo, M., Martinez, R., Sesman, M., and Guevara, L. M. (1987). The prevalence of specific psychiatric disorders in Puerto Rico. Archives of General Psychiatry, 44, 727–735CrossRefGoogle ScholarPubMed
Cheng, T. A. (1989). Sex difference in the prevalence of minor psychiatric morbidity: a social epidemiological study in Taiwan. Acta Psychiatrica Scandinavica, 80, 395–407CrossRefGoogle ScholarPubMed
Cohen, P., and Brook, J. (1987). Family factors related to the persistence of psychopathology in childhood and adolescence. Psychiatry, 50, 332–345CrossRefGoogle ScholarPubMed
Cohen, P., Cohen, J., and Brook, J. (1993a). An epidemiological study of disorders in late childhood and adolescence: 2. Persistence of disorders. Journal of Child Psychology and Psychiatry, 34, 869–877CrossRefGoogle Scholar
Cohen, P., Cohen, J., Kasen, S., Velez, C. N., Hartmark, C., Johnson, J., Rojas, M., Brook, J., and Streuning, E. L. (1993b). An epidemiological study of disorders in late childhood and adolescence: 1. Age- and gender-specific prevalence. Journal of Child Psychology and Psychiatry and Allied Disciplines, 34, 851–867CrossRefGoogle Scholar
Collu, R., and Ducharme, J. R. (1975). Role of adrenal steroids in the regulation of gonadotropin secretion at puberty. Journal of Steroid Biochemistry, 6, 869–872CrossRefGoogle ScholarPubMed
Compas, B. E., Grant, K. E., and Ey, S. (1994). Psychosocial stress and child and adolescent depression: can we be more specific? In W. M. Reynolds and H. F. Johnston (ed.), Handbook of Depression in children and adolescents (pp. 509–523). New York: PlenumCrossRef
Costello, E. J., Angold, A., Burns, B. J., Stangl, D. K., Tweed, D. L., Erkanli, A., and Worthman, C. M. (1996). The Great Smoky Mountains Study of Youth: goals, designs, methods, and the prevalence of DSM-III-R disorders. Archives of General Psychiatry, 53, 1129–1136CrossRefGoogle Scholar
Costello, E. J., Angold, A., March, J., and Fairbank, J. (1998). Life events and post-traumatic stress: the development of a new measure for children and adolescents. Psychological Medicine, 28, 1275–1288CrossRefGoogle ScholarPubMed
Costello, E. J., Costello, A. J., Edelbrock, C., Burns, B. J., Dulcan, M. K., Brent, D., and Janiszewski, S. (1988). Psychiatric disorders in pediatric primary care: prevalence and risk factors. Archives of General Psychiatry, 45, 1107–1116CrossRefGoogle ScholarPubMed
Costello, E. J., Stouthamer-Loeber, M., and DeRosier, M. (1993). Continuity and change in psychopathology from childhood to adolescence. Paper delivered at the Annual meeting of the Society for Research in Child and Adolescent Psychopathology, Santa Fe, NM
Counts, D. R., Pescovitz, O. H., Barnes, K. M., Hench, K. D., Chrousos, G. P., Sherins, R. J., Comite, F., Loriaux, D. L., and Cutler, G. B. (1987). Dissociation of adrenarche and gonadarche in precocious puberty and in isolated hypogonadotropic gypogonadism. Journal of Clinical Endocrinology and Metabolism, 64, 1174–1178CrossRefGoogle Scholar
DePeretti, E., and Forest, M. G. (1976). Unconjugated dehydroepiandrosterone plasma levels in normal subjects from birth to adolescence in human: the use of a sensitive radioimmunoassay. Journal of Clinical Endocrinology and Metabolism, 43, 962–969Google Scholar
Diggle, P. J., Liang, K. Y., and Zeger, S. L. (1994). Analysis of Longitudinal Data. Oxford: Clarendon
Dorn, L. D., Susman, E. J., Nottelmann, E. D., Inoff-Germain, E. D., and Chrousos, G. P. (1990). Perceptions of puberty: adolescent, parent, and health care personnel. Developmental Psychopathology, 26, 322–329Google Scholar
Ducharme, J. R., Forest, M. G., DePeretti, E., Sempe, M., Collu, R., and Bertrand, J. (1976). Plasma adrenal and gonadal sex steroids in human pubertal development. Journal of Clinical Endocrinology and Metabolism, 42, 458–467CrossRefGoogle ScholarPubMed
Duke, P. M., Litt, I. F., and Gross, R. T. (1980). Adolescents' self-assessment of sexual maturation. Pediatrics, 66, 918–920Google ScholarPubMed
Dunger, D. B., Villa, A. K., Matthews, D. R., Edge, J. A., Jones, J., Rothwell, C., Preece, M. A., and Robertson, W. R. (1991). Pattern of secretion of bioactive and immunoreactive gonadotropins in normal pubertal children. Clinical Endocrinology, 35, 267–275CrossRefGoogle ScholarPubMed
Dunkel, L., Alfthan, H., Stenman, U. H., and Perheentupa, J. (1990). Gonadal control of pulsatile secretion of luteinizing hormone and follicle stimulating hormone in prepubertal boys evaluated by ultrasensitive time-resolved immunofluorometric assay. Journal of Clinical Endocrinology and Metabolism, 70, 107–114CrossRefGoogle Scholar
Fleming, J. E., and Offord, D. R. (1990). Epidemiology of childhood depressive disorders: a critical review. Journal of the American Academy of Child and Adolescent Psychiatry, 29, 571–580CrossRefGoogle ScholarPubMed
Frankowski, B., Duke-Duncan, P., Guillot, A., McDougal, D., Wasserman, R., and Young, P. (1987). Young adolescents' self-assessment of sexual maturation. American Journal of Diseases of Children, 141, 385–386Google Scholar
Ge, X., Conger, R. D., and Elder, G. H. (1996). Coming of age too early: pubertal influences on girls' vulnerability to psychological distress. Child Development, 67, 3386–3400CrossRefGoogle ScholarPubMed
Goodyer, I. M. (1990). Life experience, development, and child psychopathology. Chichester, UK: John Wiley
Goodyer, I. M. (1995). Life events and difficulties: their nature and effects. In I. M. Goodyer (ed.), The depressed child and adolescent: developmental and clinical perspectives (pp. 171–193). Cambridge: Cambridge University Press
Goodyer, I., and Altham, P. M. E. (1991). Lifetime exit events and recent social and family adversities in anxious and depressed school-age children and adolescents – II. Journal of Affective Disorders, 21, 229–238CrossRefGoogle ScholarPubMed
Goodyer, I. M., Cooper, P. J., Vize, C. M., and Ashby, L. (1993). Depression in 11–16-year-old girls: the role of past parental psychopathology and exposure to recent life events. Journal of Child Psychology and Psychiatry, 34, 1103–1115CrossRefGoogle ScholarPubMed
Goodyer, I. M., Kolvin, I., and Gatzanis, S. (1986). Do age and sex influence the association between recent life events and psychiatric disorders in children and adolescents? A controlled enquiry. Journal of Child Psychology and Psychiatry, 27(5), 681–687CrossRefGoogle ScholarPubMed
Goodyer, I. M., Kolvin, I., and Gatzanis, S. (1987). The impact of recent undesirable life events on psychiatric disorders in childhood and adolescence. British Journal of Psychiatry, 151, 179–184CrossRefGoogle ScholarPubMed
Goodyer, I., Wright, C., and Altham, P. (1990). The friendships and recent life events of anxious and depressed school-age children. British Journal of Psychiatry, 156, 689–698CrossRefGoogle ScholarPubMed
Graber, J. A., Lewinsohn, P. M., Seeley, J. R., and Brooks-Gunn, J. (1997). Is psychopathology associated with the timing of pubertal development?Journal of the American Academy of Child and Adolescent Psychiatry, 36, 1768–1776CrossRefGoogle ScholarPubMed
Greif, E. B., and Ulman, K. J. (1982). The psychological impact of the menarche on early adolescent females: a review of the literature. Child Development, 53, 1413–1430CrossRefGoogle ScholarPubMed
Guyer, B., Lescohier, I., Gallagher, S. S., Hausman, A., and Azzara, C. V. (1989). Intentional injuries among children and adolescents in Massachusetts. New England Journal of Medicine, 321, 1584–1589CrossRefGoogle ScholarPubMed
Hale, P. M., Khoury, S., Foster, C. M., Beitins, I. Z., Hopwood, N. J., Marshall, J. C., and Keich, R. P. (1988). Increased luteinizing hormone pulse frequency during sleep in early to midpubertal boys. Journal of Clinical Endocrinology and Metabolism, 66, 785–791CrossRefGoogle ScholarPubMed
Halpern, C. T. R. U. J., and Suchindran, C. (1997). Testosterone predicts initiation of coitus in adolescent females. Psychosomatic Medicine, 59, 161–171CrossRefGoogle ScholarPubMed
Hankin, B. L., Abramson, L. Y., Moffitt, T. E., Silva, P. A., McGee, R., and Angell, K. E. (1998). Development of depression from preadolescence to young adulthood: emerging gender differences in a ten-year longitudinal study. Journal of Abnormal Psychology, 107, 128–140CrossRefGoogle Scholar
Hayes, F. J., and Crowley, W. F. J. (1998). Gonadotropin pulsations across development. Hormone Research, 49, 163–168CrossRefGoogle ScholarPubMed
Hayward, C., Killen, J. D., Wilson, D. M., Hammer, L. D., Litt, I. F., Kraemer, H. C., Haydel, F., Varady, A., and Taylor, C. B. (1997). Psychiatric risk associated with early puberty in adolescent girls. Journal of the American Academy of Child and Adolescent Psychiatry, 36, 255–261Google ScholarPubMed
Hutchison, J. B., Schumacher, M., Steimer, T., and Gahr, M. (1990). Are separable aromatase systems involved in hormonal regulation of the male brain?Journal of Neurobiology, 21, 743–759CrossRefGoogle ScholarPubMed
Hwu, H. G., Yeh, E. K., and Chang, L. Y. (1989). Prevalence of psychiatric disorders in Taiwan defined by the Chinese Diagnostic Interview Schedule. Acta Psychiatrica Scandinavica, 79, 136–147CrossRefGoogle ScholarPubMed
Inoff-Germain, G., Nottelmann, E. D., Arnold, G. S., and Susman, E. J. (1988). Adolescent aggression and parent–adolescent conflict: relations between observed family interactions and measures of the adolescents' general functioning. Journal of Early Adolescence, 8, 17–36CrossRefGoogle Scholar
Jensen, P. S., Richters, J., Ussery, T., Bloedau, L., and Davis, H. (1991). Child psychopathology and environmental influences: discrete life events versus ongoing adversity. Journal of the American Academy of Child and Adolescent Psychiatry, 30, 303–309CrossRefGoogle ScholarPubMed
Jorm, A. F. (1987). Sex and age differences in depression: a quantitative synthesis of published research. Australian and New Zealand Journal of Psychiatry, 21, 46–53CrossRefGoogle ScholarPubMed
Kashani, J. H., Beck, N. C., Hoeper, E. W., Fallahi, C., Corcoran, C. M., Mcallister, J. A., Rosenberg, T. K., and Reid, J. C. (1987). Psychiatric disorders in a community sample of adolescents. American Journal of Psychiatry, 144, 584–589Google Scholar
Kashani, J. H., Orvaschel, H., Rosenberg, M. A., and Reid, J. C. (1989). Psychopathology in a community sample of children and adolescents: a developmental perspective. Journal of the American Academy of Child and Adolescent Psychiatry, 28, 701–706CrossRefGoogle Scholar
Kessler, R. C., McGonagle, K. A., Nelson, C. B., Hughes, M., Swartz, M., and Blazer, D. G. (1994). Sex and depression in the National Comorbidity Survey: II. Cohort effects. Journal of Affective Disorders, 30, 15–26CrossRefGoogle ScholarPubMed
Kessler, R. C., McGonagle, K. A., Swartz, M. S., Blazer, D. G., and Nelson, C. B. (1993). Sex and depression in the National Comorbidity Survey: I. Lifetime prevalence, chronicity and recurrence. Journal of Affective Disorders, 29, 85–96CrossRefGoogle ScholarPubMed
Knochenhauer, E. S., Boots, L. R., Potter, H. D., and Azziz, R. (1998). Differential binding of estradiol and testosterone to SHBG. Relation to circulating estradiol levels. Journal of Reproductive Medicine, 43, 665–670Google ScholarPubMed
Korth-Schutz, S., Levine, L. S., and New, M. I. (1976). Serum androgens in normal prepubertal and pubertal children and in children with precocious adrenarche. Journal of Clinical Endocrinology and Metabolism, 42, 117–124CrossRefGoogle ScholarPubMed
Laflamme, N., Nappi, R. E., Drolet, G., Labrie, C., and Rivest, S. (1998). Expression and neuropeptidergic characterization of estrogen receptors (ER alpha and ER beta) throughout the rat brain: anatomical evidence of distinct roles of each subtype. Journal of Neurobiology, 36, 357–3783.0.CO;2-V>CrossRefGoogle Scholar
Laitinen-Krispijn, S., Ende, J., Hazebroek-Kampschreur, A. A. J. M., and Verhulst, F. C. (1999). Pubertal maturation and the development of behavioural and emotional problems in early adolescence. Acta Psychiatrica Scandinavica, 99, 16–25CrossRefGoogle ScholarPubMed
Landy, H., Beopple, P. A., Mansfield, M. J., Charpie, P., Schoefeld, D. I., Link, K., Romero, G., Crawford, J. D., Crigler, J. F., Blizzard, R. M., and Crowley, W. F. (1992). Sleep modulation of neuroendocrine function: developmental changes in gonadotropin-releasing hormone secretion during sexual maturation. Pediatric Research, 213, 217Google Scholar
Lashansky, G., Saenger, P., Fishman, K., Gautier, T., Mayes, D., Berg, G., DeMartino-Nardi, J., and Reiter, E. (1991). Normative data for adrenal steroidogenesis in a healthy pediatric population: age- and sex-related changes after adrenocorticotropin stimulation. Journal of Clinical Endocrinology and Metabolism, 73, 674–686CrossRefGoogle Scholar
Layman, L. C. (1995). Molecular biology in reproductive endocrinology. Current Opinion in Obstetrics and Gynecology, 75, 328–339Google Scholar
Lee, C. K., Han, J. H., and Choi, J. O. (1987). The epidemiological study of mental disorders in Korea (IX): alcoholism, anxiety, and depression. Seoul Journal of Psychiatry, 12, 183–191Google Scholar
Lee, P. A., and Migeon, C. J. (1975). Puberty in boys: correlation of plasma levels of gonadotropins (LH, FSH), androgens (testosterone, androstenedione, dehydroepiandrosterone and its sulfate), estrogens (estrone and estradiol), and progestins (progesterone and 17-hydroxyprogesterone) with physical changes. Journal of Clinical Endocrinology and Metabolism, 41, 556–562CrossRefGoogle Scholar
Lee, P. A., Xenakis, T., Winer, J., and Matsenbaugh, S. (1975). Puberty in girls: correlation of serum levels of gonadotropins, prolactin, androgens, estrogens, and progestins with physical changes. Journal of Clinical Endocrinology and Metabolism, 43, 775–784CrossRefGoogle Scholar
Lewinsohn, P. M., Gotlib, I. H., and Seeley, J. R. (1995). Adolescent psychopathology: IV. Specificity of psychosocial risk factors for depression and substance abuse in older adolescents. Journal of the American Academy of Child and Adolescent Psychiatry, 34, 1221–1229CrossRefGoogle ScholarPubMed
Lewinsohn, P. M., Hops, H., Roberts, R. E., Seeley, J. R., and Andrews, J. A. (1993). Adolescent psychopathology: I. prevalence and incidence of depression and other DSM-III-R disorders in high school students. Journal of Abnormal Psychology, 102, 133–144CrossRefGoogle ScholarPubMed
Lewinsohn, P. M., Rohde, P., and Seeley, J. R. (1998). Major depressive disorder in older adolescents: prevalence, risk factors, and clinical implications. Clinical Psychology Review, 18, 765–794CrossRefGoogle ScholarPubMed
Lu, B., Leygue, E., Dotzlaw, H., Murphy, L. J., Murphy, L. C., and Watson, P. H. (1998). Estrogen receptor-beta mRNA variants in human and murine tissues. Molecular and Cellular Endocrinology, 138, 199–203CrossRefGoogle ScholarPubMed
Marshall, J. C., Dalkin, A. C., Haisenieder, D. J., Paul, S. J., Ortolano, G. A., and Kelch, R. P. (1991). Gonadotropin-releasing hormone pulses: regulators of gonadotropin synthesis and ovulatory cycles. Recent Programs of Hormone Research, 47, 155–187Google ScholarPubMed
McCann, S. M., Kimura, M., Walczewska, A., Karanth, S., Rettori, V., and Yu, W. H. (1998). Hypothalamic control of FSH and LH by FSH-RF, cytokines, leptin and nitric oxide. Neuroimmunomodulation, 5, 193–202CrossRefGoogle ScholarPubMed
McGee, R., and Williams, S. (1988). A longitudinal study of depression in 9-year-old children. Journal of the American Academy of Child and Adolescent Psychiatry, 27, 342–348CrossRefGoogle Scholar
McGee, R., Feehan, M., Williams, S., and Anderson, J. (1992). DSM-III disorders from age 11 to age 15 years. Journal of the American Academy of Child and Adolescent Psychiatry, 31, 51–59Google ScholarPubMed
McGee, R., Feehan, M., Williams, S., Partridge, F., Silva, P. A., and Kelly, J. (1990). DSM-III disorders in a large sample of adolescents. Journal of the American Academy of Child and Adolescent Psychiatry, 29, 611–619CrossRefGoogle Scholar
Mitchner, N. A., Garlick, C., and Ben-Jonathan, N. (1998). Cellular distribution and gene regulation of estrogen receptors alpha and beta in the rat pituitary gland. Endocrinology, 139, 3976–3983CrossRefGoogle ScholarPubMed
Morris, N. M., and Udry, J. R. (1980). Validation of a self-administered instrument to assess stage of adolescent development. Journal of Youth and Adolescence, 9, 271–280CrossRefGoogle ScholarPubMed
Murphy, L. C., Dotzlaw, H., Leygue, E., Douglas, D., Coutts, A., and Watson, P. H. (1997). Estrogen receptor variants and mutations. Journal of Steroid Biochemistry and Molecular Biology, 62, 363–372CrossRefGoogle ScholarPubMed
Nolen-Hoeksema, S., Girgus, J. S., and Seligman, M. E. P. (1991). Sex differences in depression and explanatory style in children. Journal of Youth and Adolescence, 20, 233–245CrossRefGoogle ScholarPubMed
Nottelmann, E. D., Inoff-Germain, G., Susman, E. J., and Chrousos, G. P. (1990). Hormones and behavior at puberty. In J. Bancroft and J. M. Reinisch (ed.), Adolescence and puberty (pp. 88–123). Oxford: Oxford University Press
Nottelmann, E. D., Susman, E. F., Dorn, L. D., Inoff-Germain, G., Loriaux, D. L., Cutler, G. B., and Chrousos, G. P. (1987a). Developmental processes in early adolescence: relations among chronological age, pubertal stage, height, weight, and serum levels of gonadotropins, sex steroids, and adrenal androgens. Journal of Adolescent Health Care, 8, 246–260CrossRefGoogle Scholar
Nottelmann, E. D., Susman, E. J., Inoff-Germain, G., Cutler, G. B., Loriaux, D. L., and Chrousos, G. P. (1987b). Developmental processes in early adolescence: relationships between adolescent adjustment problems and chronological age, pubertal stage, and puberty-related serum hormone levels. Journal of Pediatrics, 110, 473–480CrossRefGoogle Scholar
Ojeda, S. R., and Ma, Y. J. (1998). Epidermal growth factor tyrosine kinase receptors and the neuroendocrine control of mammalian puberty. Molecular and Cellular Endocrinology, 140, 101–106CrossRefGoogle ScholarPubMed
Olsson, G. I., Nordström, M. L., Knorring, H. A., and Knorring, A. L. (1999). Adolescent depression: social network and family climate – a case-control study. Journal of Child Psychology and Psychiatry, 40, 227–237CrossRefGoogle ScholarPubMed
Olweus, D., Mattsson, A., Schalling, D., and Low, H. (1988). Circulating testosterone levels and aggression in adolescent males: a causal analysis. Psychosomatic Medicine, 50, 261–272CrossRefGoogle ScholarPubMed
Osterlund, M., Kuiper, G. G., Custafsson, J. A., and Hurd, Y. L. (1998). Differential distribution and regulation of estrogen receptor-alpha and -beta mRNA within the female rat brain. Brain Research: Molecular Brain Research, 54, 175–180Google ScholarPubMed
Paikoff, R. L., Brooks-Gunn, J., and Warren, M. P. (1991). Effects of girls' hormonal status on depressive and aggressive symptoms over the course of one year. Journal of Youth and Adolescence, 20, 191–215CrossRefGoogle ScholarPubMed
Parker, L. N., Sack, J., Fisher, D. A., and Odell, W. D. (1978). The adrenarche: Prolactin, gonadotropins, adrenal androgens, and cortisol. Journal of Clinical Endocrinology and Metabolism, 46, 396–404CrossRefGoogle ScholarPubMed
Phillips, D. J., Albertsson-Wikaland, K., Eriksson, K., and Wide, L. (1997). Changes in the isoforms of luteinizing hormone and follicle-stimulating hormone during puberty in normal children. Journal of Clinical Endocrinology and Metabolism, 82, 3103–3106CrossRefGoogle ScholarPubMed
Pickles, A., Dunn, G., and Vazquez-Barquero, J. (1995). Screening for stratification in two-phase (‘two-stage’) epidemiological surveys. Statistical Methods in Medical Research, 4, 73–89CrossRefGoogle Scholar
Pugeat, M., Crave, J. C., Tourniaire, J., and Forest, M. G. (1996). Clinical utility of sex hormone binding globulin measurement. Hormone Research, 45, 148–155CrossRefGoogle ScholarPubMed
Rasmussen, J. E., Torres-Aleman, I., MacLusky, N. J., Naftolin, F., and Robbins, R. J. (1990). The effects of estradiol on the growth patterns of estrogen receptor-positive hypothalamic cell lines. Endocrinology, 126, 235–240CrossRefGoogle ScholarPubMed
Reinherz, H. Z., Giaconia, R. M., Lefkowitz, E. S., Pakiz, B., and Frost, A. K. (1993a). Prevalence of psychiatric disorders in a community population of older adolescents. Journal of the American Academy of Child and Adolescent Psychiatry, 32, 369–377CrossRefGoogle Scholar
Reinherz, H. Z., Giaconia, R. M., Pakiz, B., Silverman, A. B., Frost, A. K., and Lefkowitz, E. S. (1993b). Psychosocial risks for major depression in late adolescence: a longitudinal community study. Journal of the American Academy of Child and Adolescent Psychiatry, 32, 1155–1163CrossRefGoogle Scholar
Reiter, E. O., Fuldauer, V. G., and Root, A. W. (1977). Secretion of the adrenal androgen, dehydroepliandrosterone sulfate, during normal infancy, childhood, and adolescence, in sick infants, and in children with endocrinologic abnormalities. Journal of Pediatrics, 90, 76–80CrossRefGoogle ScholarPubMed
Rutter, M., Graham, P., Chadwick, O. F. D., and Yule, W. (1976). Adolescent turmoil: fact or fiction?Journal of Child Psychology and Psychiatry, 17, 35–56CrossRefGoogle ScholarPubMed
Sandberg, S., Rutter, M., Pickles, A., McGuinness, D., and Angold, A. (2001). Do high-threat life events really provoke the onset of psychiatric disorder in children?Journal of Child Psychology and Psychiatry, 42, 523–532CrossRefGoogle ScholarPubMed
Schlossberger, N. M., Turner, R. A., and Irwin, C. E. (1992). Validity of self-report of pubertal maturation in early adolescents. Journal of Adolescent Health, 13, 109–113CrossRefGoogle ScholarPubMed
Seeman, M. V. (1997). Psychopathology in women and men: focus on female hormones. American Journal of Psychiatry, 154, 1641–1647CrossRefGoogle ScholarPubMed
Sizonenko, P. C., Burr, I. M., Kaplan, S. L., and Grunbach, M. M. (1970). Hormonal changes in puberty II. Correlation of serum luteinizing hormone and follicle stimulating hormone with stages of puberty and bone age in normal girls. Pediatric Research, 4, 36–45CrossRefGoogle ScholarPubMed
Sizonenko, P. C., and Paunier, L. (1975). Hormonal changes in puberty III: Correlation of plasma dehydroepiandrosterone, testosterone, FSH, and LH with stages of puberty and bone age in normal boys and girls and in patients with Addison's disease or hypogonadism or with premature or late adrenarche. Journal of Clinical Endocrinology and Metabolism, 41, 894–904CrossRefGoogle ScholarPubMed
Skuse, D. (1984). Extreme deprivation in early childhood. Journal of Child Psychology and Psychiatry, 25, 543–572CrossRefGoogle ScholarPubMed
Stattin, H., and Magnusson, D. (1990). Paths through life, vol. II, Pubertal maturation in female development. Hillsdale, NJ: Lawrence Erlbaum
Susman, E. J., Dorn, L. D., and Chrousos, G. P. (1991). Negative affect and hormone levels in young adolescents: concurrent and predictive perspectives. Journal of Youth and Adolescence, 20, 167–190CrossRefGoogle ScholarPubMed
Susman, E. J., Inoff-Germain, G., Nottelmann, E. D., Loriaux, D. L., Cutler, G. B., and Chrousos, G. P. (1987a). Hormones, emotional dispositions, and aggressive attributes in young adolescents. Child Development, 58, 1114–1134CrossRefGoogle Scholar
Susman, E. J., Nottelmann, E. D., Inoff-Germain, G., Dorn, L. D., and Chrousos, G. P. (1987b). Hormonal influences on aspects of psychological development during adolescence. Journal of Adolescent Health Care, 8, 492–504CrossRefGoogle Scholar
Susman, E. J., Nottelmann, E. D., Inoff-Germain, G. E., Dorn, L. D., Cutler, G. B., Loriaus, D. L., and Chrousos, G. P. (1985). The relation of relative hormonal levels and physical development and social-emotional behavior in young adolescents. Journal of Youth and Adolescence, 14, 245–264CrossRefGoogle ScholarPubMed
Tanner, J. M. (1962). Growth at adolescence: with a general consideration of the effects of hereditary and environmental factors upon growth and maturation from birth to maturity. Oxford: Blackwell Scientific
Veldhuis, J. D. (1996). Neuroendocrine mechanisms mediating awakening of the human gonadotropic axis in puberty. Pediatric Nephrology, 10, 304–317CrossRefGoogle ScholarPubMed
Velez, C. N., Johnson, J., and Cohen, P. (1989). A longitudinal analysis of selected risk factors of childhood psychopathology. Journal of the American Academy of Child and Adolescent Psychiatry, 28, 861–864CrossRefGoogle ScholarPubMed
Vihko, H., and Apter, D. (1980). The role of androgens in adolescent cycles. Journal of Steroid Biochemistry, 12, 369–373CrossRefGoogle ScholarPubMed
Weissman, M. M., Bland, R., Joyce, P. R., Newman, S., Wells, J. E., and Wittchen, H. U. (1993). Sex differences in rates of depression: cross-national perspectives. Journal of Affective Disorders, 29, 77–84CrossRefGoogle ScholarPubMed
Weissman, M. M., Bland, R. C., Canino, G. J., Faravelli, C., Greenwald, S., Hwu, H. G., Joyce, P. R., Karam, E. G., Lee, C. K., Lellouch, J., Lepine, J. P., Newman, S. C., Rubio-Stipec, M., Wells, J. E., Wickramaratne, P. J., Wittchen, H., and Yeh, E. K. (1996). Cross-national epidemiology of major depression and bipolar disorder. Journal of the American Medical Association, 276, 293–299CrossRefGoogle ScholarPubMed
Weissman, M. M., and Klerman, G. L. (1977). Sex differences and the epidemiology of depression. Archives of General Psychiatry, 34, 98–111CrossRefGoogle Scholar
Wells, J. E., Bushnell, J. A., Hornblow, A. R., Joyce, P. R., and Oakley-Browne, M. A. (1989). Christchurch Psychiatric Epidemiology Study. Part I, Methodology and lifetime prevalence for specific psychiatric disorders. Australian and New Zealand Journal of Psychiatry, 23, 315–326CrossRefGoogle ScholarPubMed
Wennink, J. M. B., Delemarre-van de Waal, H. A., Schoemaker, R., Schoemaker, H., and Schoemaker, J. (1989). Luteinizing hormone and follicle stimulating hormone secretion patterns in boys throughout puberty measured using highly sensitive immunoradiometric assays. Clinical Endocrinology, 31, 551–564CrossRefGoogle ScholarPubMed
Wennink, J. M. B., Delemarre-van de Waal, H. A., Schoemaker, R., Schoemaker, H., and Schoemaker, J. (1990). Luteinizing hormone and follicle stimulating hormone secretion patterns in girls throughout puberty measured using highly sensitive immunoradiometric assays. Clinical Endocrinology, 33, 333–344CrossRefGoogle ScholarPubMed
Wierman, M. E., Beardsworth, D. E., Crawford, J. D., Crigler, J. JF, Mansfield, M. J., Bode, H. H., Boepple, P. A., Kushner, D. C., and Crowley, J. WF (1986). Adrenarche and skeletal maturation during luteinizing hormone releasing hormone analogue suppression of gonadarche. Journal of Clinical Investigation, 77, 121–126CrossRefGoogle ScholarPubMed
Williamson, D. E., Birmaher, B., Frank, E., Anderson, B., Matty, M. K., and Kupfer, D. J. (1998). Nature of life events and difficulties in depressed adolescents. Journal of the American Academy of Child and Adolescent Psychiatry, 37, 1049–1057CrossRefGoogle ScholarPubMed
Wittchen, H.-U., Essau, C. A., Zerssen, D., Krieg, J. C., and Zaudig, M. (1992). Lifetime and six-month prevalence of mental disorders in the Munich Follow-up Study. European Archives of Psychiatry and Clinical Neuroscience, 241, 247–258CrossRefGoogle ScholarPubMed
Worthman, C. (1999). Epidemiology of human development. In C. Panter-Brick and C. Worthman (ed.), Hormones, health, and behavior: a socio-ecological and lifespan perspective (pp. 47–104). Cambridge: Cambridge University Press
Worthman, C. M., and Stallings, J. F. (1997a). Hormone measures in finger-prick blood spot samples: new field methods for reproductive endocrinology. American Journal of Physical Anthropology, 103, 1–213.0.CO;2-V>CrossRefGoogle Scholar
Worthman, C. M., and Stallings, J. F. (1997b). Hormone measures in finger-prick blood spot samples: new field methods for reproductive endocrinology. American Journal of Physical Anthropology, 103, 1–213.0.CO;2-V>CrossRefGoogle Scholar
Wu, F. C., Butler, G. E., Kelnar, C. J. H., and Sellar, R. E. (1990). Patterns of pulsatile luteinizing hormone secretion before and during the onset of puberty in boys: a study using an immunoradiometric assay. Journal of Clinical Endocrinology and Metabolism, 70, 629–637CrossRefGoogle ScholarPubMed
Young, E., and Korszun, A. (1998). Psychoneuroendocrinology of depression. Hypothalamic pituitary-gonadal axis. Psychiatric Clinics of North America, 21, 309–323CrossRefGoogle ScholarPubMed
Zeginiadou, T., Kolias, S., Kouretas, D., and Antonoglou, O. (1997). Nonlinear binding of sex steroids to albumin and sex hormone binding globulin. European Journal of Drug Metabolism and Pharmacokinetics, 22, 229–235CrossRefGoogle ScholarPubMed

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  • Puberty and depression
    • By Adrian Angold, Associate Professor of Psychiatry and Behavioral Sciences, Duke University Medical Center, Carol Worthman, Samuel Candler Dobbs Professor of Anthropology, Emory University, E. Jane Costello, Professor of Medical Psychology, Duke University Medical Center
  • Edited by Chris Hayward, Stanford University, California
  • Book: Gender Differences at Puberty
  • Online publication: 22 September 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511489716.009
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  • Puberty and depression
    • By Adrian Angold, Associate Professor of Psychiatry and Behavioral Sciences, Duke University Medical Center, Carol Worthman, Samuel Candler Dobbs Professor of Anthropology, Emory University, E. Jane Costello, Professor of Medical Psychology, Duke University Medical Center
  • Edited by Chris Hayward, Stanford University, California
  • Book: Gender Differences at Puberty
  • Online publication: 22 September 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511489716.009
Available formats
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  • Puberty and depression
    • By Adrian Angold, Associate Professor of Psychiatry and Behavioral Sciences, Duke University Medical Center, Carol Worthman, Samuel Candler Dobbs Professor of Anthropology, Emory University, E. Jane Costello, Professor of Medical Psychology, Duke University Medical Center
  • Edited by Chris Hayward, Stanford University, California
  • Book: Gender Differences at Puberty
  • Online publication: 22 September 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511489716.009
Available formats
×