Book contents
- Fundamentals of Nanomedicine
- Fundamentals of Nanomedicine
- Copyright page
- Dedication
- Contents
- Preface
- Acknowledgments
- 1 The Need for New Perspectives in Medicine
- 2 Nanomedicine: Single-Cell Medicine
- 3 Targeted Drug Delivery
- 4 Drug Delivery Cell Entry Mechanisms
- 5 Nanomaterial Cores for Noninvasive Imaging
- 6 Attaching Biomolecules to Nanoparticles
- 7 Characterizing Nanoparticles
- 8 Nanomedicine Drug Dosing
- 9 Nanodelivery of Therapeutic Genes
- 10 Assessing Nanomedical Therapies at the Single-Cell Level
- 11 Nanotoxicity at the Single-Cell Level
- 12 Designing Nanodelivery Systems for In Vivo Use
- 13 Designing and Testing Nanomedical Devices
- 14 Quality Assurance and Regulatory Issues of Nanomedicine for the Pharmaceutical Industry
- References
- Index
9 - Nanodelivery of Therapeutic Genes
Published online by Cambridge University Press: 08 March 2022
Book contents
- Fundamentals of Nanomedicine
- Fundamentals of Nanomedicine
- Copyright page
- Dedication
- Contents
- Preface
- Acknowledgments
- 1 The Need for New Perspectives in Medicine
- 2 Nanomedicine: Single-Cell Medicine
- 3 Targeted Drug Delivery
- 4 Drug Delivery Cell Entry Mechanisms
- 5 Nanomaterial Cores for Noninvasive Imaging
- 6 Attaching Biomolecules to Nanoparticles
- 7 Characterizing Nanoparticles
- 8 Nanomedicine Drug Dosing
- 9 Nanodelivery of Therapeutic Genes
- 10 Assessing Nanomedical Therapies at the Single-Cell Level
- 11 Nanotoxicity at the Single-Cell Level
- 12 Designing Nanodelivery Systems for In Vivo Use
- 13 Designing and Testing Nanomedical Devices
- 14 Quality Assurance and Regulatory Issues of Nanomedicine for the Pharmaceutical Industry
- References
- Index
Summary
Typically, there is an optimal dose for treating a diseased cell. But most conventional drug delivery systems have either exponential or biexponential decay characteristics. So-called timed-release drugs create a sawtooth drug delivery pattern, which is a big improvement but still less than optimal. What we really want is to be able to hold the drug delivery to as close to the optimal dose as possible over time. This can best be done using nanomedical systems with biosensing and feedback control systems.
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- Information
- Fundamentals of Nanomedicine , pp. 159 - 185Publisher: Cambridge University PressPrint publication year: 2022