This chapter focuses on six groups that were forced to migrate and become bound laborers at English sites of overseas expansion. It examines the poor, criminals, and prisoners of war from the British Isles forced into servitude, the indigenous people of the circum-Caribbean who wound up enslaved, enslaved West Africans from the Gold Coast, people sold into slavery in India during times of famine (especially on the Coromandel Coast), the Malagasy people of Madagascar sold for firearms, and the indigenous peoples of the Indonesian archipelago forced to labor for the East India Company. This chapter will stress the political and socioeconomic conditions that made these groups vulnerable to enslavement or other closely adjacent forms of bondage. The chapter highlights the ways in which the Little Ice Age created famine and political and social upheaval that shaped forced and free migration. It also emphasizes the added political destabilization that came with the expansion of global trade, the introduction of firearms as a trade good, and competition for access to coastal trades. This destabilization and change made people in the tropics more vulnerable to enslavement.