from Section 1: - General Principles
Published online by Cambridge University Press: 21 October 2019
Despite advances in neonatal intensive care, prematurity remains an unsolved clinical challenge and a leading cause of infant morbidity and mortality [1]. Approximately 6% of all live births in the USA are considered extremely preterm (delivery at less than 28 weeks’ gestation), and the incidence of prematurity has slowly risen over the past decade [2]. Prematurity is thought to account for one-third of infant mortality [3], one-half of cerebral palsy, and 80% of survivors born at 22–28 weeks’ gestation will suffer at least one major co-morbidity [4].
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