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Chapter 35 - Ovarian Allotransplantation

from Section 9 - New Research and Technologies

Published online by Cambridge University Press:  27 March 2021

Jacques Donnez
Affiliation:
Catholic University of Louvain, Brussels
S. Samuel Kim
Affiliation:
University of Kansas School of Medicine
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Summary

The transplantation of endocrine organs can be regarded as the oldest form of transplantation in modern medical history. By the end of the nineteenth and beginning of the twentieth centuries, a large research focus was set on endocrine transplantations. Before the complex endocrine secretion and function was even understood, researchers attempted to cure endocrine diseases and infertility through transplantation of the endocrine glands and gonads. Hence, most endocrine organs have been transplanted in that period, including the thyroid [1], the adrenal gland [2], the testis [3] and the ovary [4]. Even though the principles of transplant rejection have not been understood at that time, researchers already noticed successful transplantations almost exclusively in experiments with autografts. The first published allogeneic ovarian transplantations in animals have been performed by Paul Bert in the sixties of the nineteenth century [5].

Type
Chapter
Information
Fertility Preservation
Principles and Practice
, pp. 404 - 409
Publisher: Cambridge University Press
Print publication year: 2021

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References

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