Book contents
- Fertility Preservation
- Fertility Preservation
- Copyright page
- Dedication
- Contents
- Contributors
- Foreword
- Foreword
- Preface
- Section 1 Introduction
- Section 2 Reproductive Biology and Cryobiology
- Section 3 Fertility Preservation in Cancer and Non-Cancer Patients
- Section 4 Fertility Preservation Strategies in the Male
- Section 5 Fertility Preservation Strategies in the Female: Medical/Surgical
- Section 6 Fertility Preservation Strategies in the Female: ART
- Section 7 Ovarian Cryopreservation and Transplantation
- Section 8 In Vitro Follicle Culture
- Section 9 New Research and Technologies
- Chapter 33 The Artificial Ovary
- Chapter 34 Uterus Transplantation
- Chapter 35 Ovarian Allotransplantation
- Chapter 36 Allotransplantation of Human Ovarian Tissue
- Chapter 37 Predicting Ovarian Futures
- Section 10 Ethical, Legal, and Religious Issues
- Index
- References
Chapter 33 - The Artificial Ovary
from Section 9 - New Research and Technologies
Published online by Cambridge University Press: 27 March 2021
- Fertility Preservation
- Fertility Preservation
- Copyright page
- Dedication
- Contents
- Contributors
- Foreword
- Foreword
- Preface
- Section 1 Introduction
- Section 2 Reproductive Biology and Cryobiology
- Section 3 Fertility Preservation in Cancer and Non-Cancer Patients
- Section 4 Fertility Preservation Strategies in the Male
- Section 5 Fertility Preservation Strategies in the Female: Medical/Surgical
- Section 6 Fertility Preservation Strategies in the Female: ART
- Section 7 Ovarian Cryopreservation and Transplantation
- Section 8 In Vitro Follicle Culture
- Section 9 New Research and Technologies
- Chapter 33 The Artificial Ovary
- Chapter 34 Uterus Transplantation
- Chapter 35 Ovarian Allotransplantation
- Chapter 36 Allotransplantation of Human Ovarian Tissue
- Chapter 37 Predicting Ovarian Futures
- Section 10 Ethical, Legal, and Religious Issues
- Index
- References
Summary
Since the first publications on the artificial ovary, many advances have been made. At that time, no studies had yet proved the feasibility of the concept, so it might have appeared provocative to unable to propose this option as a future fertility restoration approach for women unable to undergo ovarian tissue transplantation. Today, different artificial ovary prototypes demonstrate that this technique is able to restore both endocrine and reproductive functions in a murine model, producing healthy pups. However, with a view to future clinical application, further studies with human ovarian tissue and human follicles are essential. The aim of this chapter is to highlight the latest developments and advances in the field, as well as future directions for prompt translation to a clinical setting.
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- Information
- Fertility PreservationPrinciples and Practice, pp. 381 - 393Publisher: Cambridge University PressPrint publication year: 2021