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20 - Obstetric and perinatal outcomes in pregnancies conceived following oocyte cryopreservation

from Section 4 - Cryopreservation of oocytes

Published online by Cambridge University Press:  06 July 2010

Ri-Cheng Chian
Affiliation:
McGill University, Montréal
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Summary

This chapter discusses the pregnancy outcomes in assisted reproductive technologies (ART). It focuses on the current evidence regarding pregnancy and perinatal outcomes in pregnancies conceived following oocyte cryopreservation. Although the great majority of singleton ART pregnancies are uncomplicated, there is recent evidence of higher rates of adverse pregnancy outcomes in singleton ART pregnancies compared with spontaneously conceived singleton gestations. Women with in vitro fertilization (IVF)-conceived singletons are at increased risk of pre-eclampsia, gestational diabetes, placenta previa, and perinatal mortality. As cryopreservation techniques improve and pregnancy and implantation rates increase, the number of embryos transferred will decrease and the incidence of multiple pregnancy following oocyte cryopreservation will fall. National or international registries (either within established ART registries or as stand-alone registries) for oocyte cryopreservation should be established and continue to collect treatment, pregnancy outcome, and childhood data over the next several decades.
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Publisher: Cambridge University Press
Print publication year: 2010

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