This book explores the intersection of theology and women’s studies, centering around the influential figure of Fatima within Shiʿi theology. By examining Fatima’s sacred role and her impact on empowering women and political minorities, the manuscript offers a textual analysis of her sermon. It unveils the early roots of female empowerment and agency in Islam, effectively challenging prevailing Western beliefs. Contrary to common assumptions, it demonstrates that God-centric Muslim women possess the capacity, willingness, and authority to actively engage in promoting social justice and advocating for transformative change. Through this transformative praxis, the book aims to empower the female condition within Muslim cultures and societies. By embracing a nuanced perspective, it redefines the dynamic role of women, emphasizing the critical connection between faith, gender, and inclusivity. This exploration promises to reshape academic discourse around Islamic feminist theology and inspirational premodern Muslim women as initiators of social change within cultural contexts.