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3 - Neural Dynamics

Published online by Cambridge University Press:  30 May 2024

Geir Halnes
Affiliation:
Norwegian University of Life Sciences
Torbjørn V. Ness
Affiliation:
Norwegian University of Life Sciences
Solveig Næss
Affiliation:
Universitetet i Oslo
Espen Hagen
Affiliation:
Universitetet i Oslo
Klas H. Pettersen
Affiliation:
The Norwegian Artificial Intelligence Research Consortium
Gaute T. Einevoll
Affiliation:
Norwegian University of Life Sciences
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Summary

The standard two-step scheme for modeling extracellular signals is to first compute the neural membrane currents using multicompartment neuron models (step 1) and next use the volume-conductor theory to compute the extracellular potential resulting from these membrane currents (step 2). We here give a brief introduction to the multicompartment modeling of neurons in step 1. The formalism presented, which has become the gold standard within the field, combines a Hodgkin-Huxley-type description of membrane mechanisms with the cable theory description of the membrane potential in dendrites and axons.

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Electric Brain Signals
Foundations and Applications of Biophysical Modeling
, pp. 41 - 78
Publisher: Cambridge University Press
Print publication year: 2024

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