Published online by Cambridge University Press: 27 June 2019
Ketamine and related compounds, such as esketamine, are of relevance to ECT practice for several reasons. First, as a drug with marked rapid antidepressant activity in people with treatment resistant depression (TRD), it may become an alternative to ECT in some cases. Second, ECT suites are a suitable setting for intravenous or other routes of directly observed therapy and ECT staff have experience with this patient group. Third, there may be synergy between ketamine and neuromodulatory therapies such as TMS.
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