Don DeLillo is not considered a regionalist writer in the American literary tradition, yet this chapter explores a primary geographical region in which his novels are often set, the Southwest, with emphasis on both urban and desert landscapes. DeLillo's early novel Running Dog and his later work Point Omega are the chapter's main examples. While DeLillo is not a regionalist in any conventional sense, the chapter explains how DeLillo's fiction disrupts literary conventions of time and space in his depiction of the American Southwest, thereby asking readers to consider a reading of DeLillo in which postmodern literary experimentalism combines with a punk rock aesthetic rooted in graffiti and political art (hence the chapter's title, which borrows a a lyric from the Misfits, a band named after a famous mid-century Western film).