Skip to main content Accessibility help
×
Hostname: page-component-78c5997874-fbnjt Total loading time: 0 Render date: 2024-11-03T02:26:29.235Z Has data issue: false hasContentIssue false

Chapter 19 - Treatment and prognosis of acute disseminated encephalomyelitis

from Section 4 - ADEM

Published online by Cambridge University Press:  11 April 2011

Dorothée Chabas
Affiliation:
University of California, San Francisco
Emmanuelle L. Waubant
Affiliation:
University of California, San Francisco
Get access

Summary

This chapter focuses on the treatment of acute disseminated encephalomyelitis (ADEM) in children. Early case series reported multiple regimens of corticosteroids for ADEM, including both oral and intravenous therapies, depending on the severity of neurologic impairment. A relapse may be associated with corticosteroid withdrawal or may signify an alternative diagnosis, such as recurrent ADEM, multiphasic disseminated encephalomyelitis, or multiple sclerosis (MS). Intravenous immunoglobulins (IVIg) have been used successfully as an alternative therapy for autoimmune diseases including ADEM. Plasma exchange, has been used to treat many neurologic diseases including Guillain-Barrésyndrome. The location of the lesions can cause a variety of neurologic deficits requiring additional treatment, such as anti-epileptic drugs for children with seizures and mechanical ventilation for brainstem or upper cervical cord involvement. The prognosis for children with ADEM is generally favorable. The clinical presentation and time to recovery are quite variable in children with ADEM.
Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×