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13 - Experience-Dependent Plasticity in the Hippocampus

from Part II - Applications

Published online by Cambridge University Press:  18 September 2020

By
Greg L. West  and
Véronique D. Bohbot
Edited by
Laurence J. Kirmayer ,
Carol M. Worthman ,
Shinobu Kitayama ,
Robert Lemelson  and
Constance A. Cummings
Laurence J. Kirmayer
Affiliation:
McGill University, Montréal
Carol M. Worthman
Affiliation:
Emory University, Atlanta
Shinobu Kitayama
Affiliation:
University of Michigan, Ann Arbor
Robert Lemelson
Affiliation:
University of California, Los Angeles
Constance A. Cummings
Affiliation:
The Foundation for Psychocultural Research
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Summary

Life experiences have been associated with significant changes in brain structure and functioning. This experience-dependent plasticity is thought to reflect the capacity of our nervous systems to adapt to environmental demands, and ultimately shape cognition. This chapter focuses on how such experiences and environment can specifically impact the hippocampus, a structure important for learning, memory, and healthy cognition. The hippocampal memory system maintains a competitive relationship with other memory systems, in particular the caudate nucleus of the striatum, part of the basal ganglia. Specific types of behavior, such as spatial-based vs. response-based navigational strategies, can influence these memory systems both positively and negatively and lead to long-term neuroplastic changes. Overreliance on non-hippocampus dependent navigational strategies is associated with a reduction in hippocampus volume and activity across the lifespan. Emerging research is now pointing to the wide use of electronic devices – GPS, smartphones, and video games – as a contributing factor to greater reliance on non-hippocampus dependent memory. Given the limited, but concerning, evidence that reliance on electronic devices can interact with already established factors related to underuse of the hippocampal memory system, further study is needed to better understand how these imbalances occur and how they can be mitigated.

Keywords

hippocampusstriatumplasticitycognitive trainingmemorynavigationstressaginggenotypingvideo games
Type
Chapter
Information
Culture, Mind, and Brain
Emerging Concepts, Models, and Applications
 , pp. 375 - 388
Publisher: Cambridge University Press
Print publication year: 2020

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